2. Gene
  3. S100b - S100 calcium binding protein B Gene

S100b - S100 calcium binding protein B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: S100P

基因 ID: 25742 | 基因类型: protein coding

关于 S100b

功能概要

Enables RAGE receptor binding activity; identical protein binding activity; and metal ion binding activity. Involved in several processes, including long-term synaptic potentiation; negative regulation of skeletal muscle cell differentiation; and positive regulation of myelination. Located in cytoplasm and extracellular space. Used to study demyelinating disease. Biomarker of several diseases, including bipolar disorder; borna disease; brain disease (multiple); mental depression; and sleep apnea. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B). [provided by Alliance of Genome Resources, Apr 2022]

S100b 基因产物(1)

mRNA Protein Name
NM_013191.2 NP_037323.1 protein S100-B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RAGE receptor binding IPI
IPI: 通过物理相互作用推断
19910580 RGD
enables calcium ion binding IDA
IDA: 通过直接分析推断
14621986 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
18949447 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
19910580 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
18445708 RGD
enables zinc ion binding IDA
IDA: 通过直接分析推断
14621986 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in astrocyte differentiation IEP
IEP: 通过表达模式推断
19147496 RGD
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
19910580 RGD
involved in long-term synaptic potentiation IEP
IEP: 通过表达模式推断
21546003 RGD
involved in negative regulation of skeletal muscle cell differentiation IMP
IMP: 通过突变表型推断
20069545 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
17639288 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
2229184 RGD
involved in positive regulation of myelination IMP
IMP: 通过突变表型推断
25536222 RGD
involved in positive regulation of synaptic transmission IMP
IMP: 通过突变表型推断
12428274 RGD
involved in regulation of cell shape IMP
IMP: 通过突变表型推断
2229184 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
16112204 RGD
involved in response to methylmercury IEP
IEP: 通过表达模式推断
21783483 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
21098642 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

protein S100-B

S-100 protein beta chain

S-100 protein subunit beta

S100 calcium-binding protein, beta (neural)

S100 protein, beta polypeptide, neural

S100b 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
S100b P04631 Ager Rattus norvegicus Q63495
Anti Bait CoIP
19910580
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16918A Heptamidine dimethanesulfonate Inhibitor 99.82% 否
HY-W585874 Nε-(Carboxyethyl)lysine Modulator 99.9% 否
HY-16918 Heptamidine / 否
HY-RS12387 S100B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16975 S100b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23418 S100b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens S100b NCBI NCBI:6285
Canis familiaris S100b NCBI NCBI:491615
Mus musculus S100b NCBI NCBI:20203
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