1. Gene
  2. Ehd2 - EH-domain containing 2 Gene

Ehd2 - EH-domain containing 2 Gene

种属: Mus musculus

同用名: C130052H20Rik

基因 ID: 259300 | 基因类型: protein coding

关于 Ehd2

功能概要

Enables identical protein binding activity and protein domain specific binding activity. Involved in several processes, including plasma membrane tubulation; positive regulation of endocytic recycling; and positive regulation of myoblast fusion. Acts upstream of or within cortical actin Cytoskeleton organization and endocytosis. Located in caveola; cytosol; and perinuclear region of cytoplasm. Is extrinsic component of membrane. Is expressed in aorta endothelium; blood vessel; brown fat; lymphatic vessel endothelium; and mesenteric artery. Orthologous to human EHD2 (EH domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Ehd2 基因产物(1)

mRNA Protein Name
NM_153068.3 NP_694708.2 EH domain-containing protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17914359 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15247266 MGI
enables protein domain specific binding IDA
IDA: 通过直接分析推断
14676205 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cortical actin cytoskeleton organization IDA
IDA: 通过直接分析推断
15247266 MGI
acts upstream of or within endocytosis IDA
IDA: 通过直接分析推断
14676205 MGI
involved in plasma membrane tubulation IDA
IDA: 通过直接分析推断
24508342 MGI
involved in positive regulation of endocytic recycling IMP
IMP: 通过突变表型推断
21177873 MGI
involved in positive regulation of myoblast fusion IMP
IMP: 通过突变表型推断
21177873 MGI
involved in protein localization to plasma membrane IDA
IDA: 通过直接分析推断
21177873 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in caveola IDA
IDA: 通过直接分析推断
24508342 MGI
located in cytosol IDA
IDA: 通过直接分析推断
24508342 MGI
located in membrane IDA
IDA: 通过直接分析推断
14676205 MGI
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
20489164 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15247266 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

EH domain-containing protein 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ehd2 NCBI NCBI:30846