EGFL6 - EGF like domain multiple 6 Gene

中文名称：EGF 样域倍数 6

种属: Homo sapiens

同用名: W80; MAEG

关于 EGFL6

功能概要

该基因编码表皮生长因子 (EGF) 重复超家族的成员。该超家族成员的特征是存在 EGF 样重复序列，并且通常参与细胞周期、增殖和发育过程的调节。基因产物含有信号肽，提示其被分泌；一个 EGF 重复区域，由 4 个完整的 EGF 样重复和 1 个部分 EGF 样重复组成，其中 3 个具有钙结合共有序列； arg-gly-asp 整合素结合基序；和 MAM 结构域，据信它具有粘合功能。该基因在发育早期表达，已在肺和脑膜瘤中检测到其表达。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp Integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008]