PPP1R16B - protein phosphatase 1 regulatory subunit 16B Gene

中文名称：蛋白磷酸酶 1 调节亚基 16B

种属: Homo sapiens

同用名: TIMAP; ANKRD4

关于 PPP1R16B

功能概要

该基因编码的蛋白质与膜相关，包含五个锚蛋白重复序列、一个蛋白磷酸酶 1 相互作用结构域和一个羧基末端 CAAX 框结构域。编码蛋白的合成受到转化生长因子 β-1 的抑制。该蛋白质可通过其 CAAX 盒结构域与膜结合，并可通过与蛋白磷酸酶-1 的相互作用充当信号分子。选择性剪接导致编码不同亚型的多个转录变体，这些亚型可能经历类似的加工以产生成熟蛋白质。[RefSeq 提供，2015 年 9 月]

The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]