2. Gene
  3. GGTA1 - glycoprotein alpha-galactosyltransferase 1 (inactive) Gene

GGTA1 - glycoprotein alpha-galactosyltransferase 1 (inactive) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：糖蛋白 α-半乳糖基转移酶 1 (无活性)

种属: Homo sapiens

同用名: GGTA; GLYT2; GGTA1P; a1/3GTP

基因 ID: 2681 | 基因类型: protein coding

关于 GGTA1

Cytogenetic location: 9q33.2 Genomic coordinates (GRCh38): 9:121,444,990-121,499,844 (from NCBI)

This gene has 5 transcripts (splice variants) and 7 orthologues. Ubiquitous expression in salivary gland (RPKM 23.8), bone marrow (RPKM 17.7) and 24 other tissues.

功能概要

α-1,3-半乳糖基转移酶 (GGTA1) 是一种存在于除人类、猿类和旧大陆猴以外的大多数哺乳动物体内的酶。该基因被认为编码一种截短的非酶促形式的 GGTA1 蛋白，该蛋白缺乏 C 端催化结构域。 GGTA1 蛋白在人体中的异常表达会导致自身免疫性疾病，有时还会导致生殖细胞肿瘤。[RefSeq 提供，2020 年 5 月]

Alpha-1,3-galactosyltransferase (GGTA1) is an enzyme present in most mammals except man, apes, and Old World monkeys. This gene is thought to encode a truncated, non-enzymatic form of the GGTA1 protein that lacks the C-terminal catalytic domain. Aberrant expression of the GGTA1 protein in man can lead to autoimmune diseases and sometimes germ cell tumors. [provided by RefSeq, May 2020]

GGTA1 基因产物(4)

mRNA Protein Name
NM_001382584.1 NP_001369513.1 inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase
NM_001382585.1 NP_001369514.1 inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase
NM_001382586.1 NP_001369515.1 inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase
NM_001382587.1 NP_001369516.1 inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase
蛋白主名 其他名称

inactive N-acetyllactosaminide alpha-1,3-galactosyltransferase

glycoprotein alpha-galactosyltransferase 1, pseudogene

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70052 alpha-1,3-Galactosyltransferase (a1,3GalT) / 否
HY-RS05407 GGTA1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19435 Ggta1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25926 Ggta1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26403 Ggt5 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus GGTA1 MGD MGI:95704
Rattus norvegicus GGTA1 RGD RGD:629476
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