1. Gene
  2. GFER - Gfer growth factor, augmenter of liver regeneration Gene

GFER - Gfer growth factor, augmenter of liver regeneration Gene

种属: Rattus norvegicus

同用名: ALR

基因 ID: 27100 | 基因类型: protein coding

关于 GFER

功能概要

Enables flavin-linked sulfhydryl oxidase activity. Involved in several processes, including cellular response to actinomycin D; liver regeneration; and negative regulation of cell death. Located in cytosol; extracellular space; and mitochondrion. Used to study acute kidney failure. Biomarker of acute kidney failure; cryptorchidism; and ureteral obstruction. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Orthologous to human GFER (growth factor, augmenter of liver regeneration). [provided by Alliance of Genome Resources, Apr 2022]

GFER 基因产物(1)

mRNA Protein Name
NM_013222.2 NP_037354.2 FAD-linked sulfhydryl oxidase ALR
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables flavin-dependent sulfhydryl oxidase activity IDA
IDA: 通过直接分析推断
11346147 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to actinomycin D IEP
IEP: 通过表达模式推断
23073658 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
23073658 RGD
involved in cellular response to toxic substance IEP
IEP: 通过表达模式推断
23073658 RGD
involved in cellular response to tumor necrosis factor IEP
IEP: 通过表达模式推断
23073658 RGD
involved in liver regeneration IMP
IMP: 通过突变表型推断
24880092 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
18272248 RGD
involved in negative regulation of natural killer cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
9021955 RGD
involved in positive regulation of DNA biosynthetic process IDA
IDA: 通过直接分析推断
16937468 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
23073658 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
10216127 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

FAD-linked sulfhydryl oxidase ALR

FAD-linked sulfhydryl oxidase ALR-like

augmenter of liver regeneration

growth factor, erv1 homolog

growth factor, erv1-like (augmenter of liver regeneration)

translation initiation factor IF-2-like

重组 GFER 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71571 GFER Protein, Rat (His-SUMO) Q63042 (M1-D198) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens GFER NCBI NCBI:2671