2. Gene
  3. DKKL1 - dickkopf like acrosomal protein 1 Gene

DKKL1 - dickkopf like acrosomal protein 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：dickkopf 样顶体蛋白 1

种属: Homo sapiens

同用名: SGY; CT34; SGY1; SGY-1

基因 ID: 27120 | 基因类型: protein coding

关于 DKKL1

Cytogenetic location: 19q13.33 Genomic coordinates (GRCh38): 19:49,360,515-49,375,116 (from NCBI)

This gene has 6 transcripts (splice variants) and 92 orthologues. Restricted expression toward testis (RPKM 49.6).

功能概要

dickkopf 蛋白家族与 Wnt 信号通路相互作用，其成员的特征在于两个保守的富含半胱氨酸的结构域。该基因编码的分泌蛋白与 dickkopf-3 蛋白的序列相似性较低。已经为该基因发现了编码不同亚型的多个选择性剪接的转录物变体。[RefSeq 提供，2010 年 10 月]

The dickkopf protein family interacts with the Wnt signaling pathway and its members are characterized by two conserved cysteine-rich domains. This gene encodes a secreted protein that has low sequence similarity to the dickkopf-3 protein. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

DKKL1 基因产物(3)

mRNA Protein Name
NM_001197301.2 NP_001184230.1 dickkopf-like protein 1 isoform 2 precursor
NM_001197302.2 NP_001184231.1 dickkopf-like protein 1 isoform 3
NM_014419.4 NP_055234.1 dickkopf-like protein 1 isoform 1 precursor
蛋白主名 其他名称

dickkopf-like protein 1

cancer/testis antigen 34

关联疾病

疾病名称 别名
Rectum Adenocarcinoma

Rectal Adenocarcinoma

Adenocarcinoma Of Rectum
Rectal Benign Neoplasm

Neoplasm Of Rectum

Rectal Tumor

Rectum Neoplasm

Neoplasm Of The Rectum

Rectal Neoplasms

Primary Rectal Cancer

Rectal Ampulla Cancer

Cancer Of The Rectum

Carcinoma Of Rectum

Primary Malignant Neoplasm Of Rectum

Rectal Cancer

Rectal Carcinoma
Trachea Carcinoma

Pancoast Tumor

Carcinoma Of The Trachea

Pancoast'S Tumor

Malignant Superior Sulcus Tumor

Malignant Superior Sulcus Tumour

Pancoast Tumour

Pancoast'S Syndrome

Pancoast'S Tumour

Pulmonary Sulcus Tumor

Pulmonary Sulcus Tumour

Superior Pulmonary Sulcus Syndrome

Pancoast Syndrome
Rectum Cancer

Malignant Neoplasm Of Rectum

Rectal Cancer

Cancer Of Rectum

Carcinoma Of Rectum

Carcinoma Of The Rectum

Malignant Rectal Tumor

Malignant Rectum Tumor

Malignant Tumor Of Rectum

Rectal Carcinoma

Rectal Cancers

Cancer, Rectal
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03791 DKKL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20011 Dkkl1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26514 Dkkl1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DKKL1 RGD RGD:1563523
Felis catus DKKL1 VGNC VGNC:61507
Canis familiaris DKKL1 VGNC VGNC:39973
Macaca mulatta DKKL1 VGNC VGNC:109615
Bos taurus DKKL1 VGNC VGNC:28083
Mus musculus DKKL1 MGD MGI:1354963
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