1. Gene
  2. SIGLEC9 - sialic acid binding Ig like lectin 9 Gene

SIGLEC9 - sialic acid binding Ig like lectin 9 Gene

中文名称:唾液酸结合 Ig样凝集素 9

种属: Homo sapiens

同用名: CD329; CDw329; FOAP-9; siglec-9; OBBP-LIKE

基因 ID: 27180 | 基因类型: protein coding

关于 SIGLEC9

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,119,778-51,136,263 (from NCBI)

This gene has 3 transcripts (splice variants), 84 orthologues and 16 paralogues. Broad expression in appendix (RPKM 3.6), spleen (RPKM 2.9) and 15 other tissues.

功能概要

预测具有单糖结合活性和唾液酸结合活性。预计参与细胞粘附。预计在炎症反应的负调节和吞噬作用、吞噬的负调节的上游或内部起作用。预计位于质膜外侧。预计在质膜上有活性。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable monosaccharide binding activity and sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within negative regulation of inflammatory response and negative regulation of phagocytosis, engulfment. Predicted to be located in external side of plasma membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SIGLEC9 基因产物(2)

mRNA Protein Name
NM_001198558.1 NP_001185487.1 sialic acid-binding Ig-like lectin 9 isoform 1 precursor
NM_014441.3 NP_055256.1 sialic acid-binding Ig-like lectin 9 isoform 2 precursor

SIGLEC9 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (26 - 127)

Ig_3

Ig_3: Immunoglobulin domain (151 - 216)

Ig_2

Ig_2: Immunoglobulin domain (260 - 335)

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  • 463 a.a.
蛋白主名 其他名称

sialic acid-binding Ig-like lectin 9

protein FOAP-9

重组 SIGLEC9 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70739 Siglec-9 Protein, Human (HEK293, His) AAH35365.2 (Q18-G348) ≥95%
HY-P78039 Siglec-9 Protein, Human (HEK293, Fc) Q9Y336 (Q18-G348) ≥95%
HY-P78040 Siglec-9 Protein, Human (HEK293, His-Avi) Q9Y336 (Q18-G348) ≥95%
HY-P701040 Siglec-9 Protein, Human (Biotinylated, HEK293, His-Avi) Q9Y336-1 (Q18-G348) ≥95%

直系同源

种属 基因名 来源 基因 ID
Mus musculus SIGLEC9 MGD MGI:1932475