2. Gene
  3. Pdk4 - pyruvate dehydrogenase kinase, isoenzyme 4 Gene

Pdk4 - pyruvate dehydrogenase kinase, isoenzyme 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 27273 | 基因类型: protein coding

关于 Pdk4

功能概要

Predicted to enable ATP binding activity and pyruvate dehydrogenase (acetyl-transferring) kinase activity. Involved in several processes, including Insulin Receptor signaling pathway; regulation of bone resorption; and regulation of fatty acid metabolic process. Located in mitochondrial inner membrane. Is expressed in several structures, including brain; genitourinary system; gut; respiratory system; and skin. Orthologous to human PDK4 (pyruvate dehydrogenase kinase 4). [provided by Alliance of Genome Resources, Apr 2022]

Pdk4 基因产物(1)

mRNA Protein Name
NM_013743.2 NP_038771.1 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
16606348 MGI
involved in insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
19627255 MGI
involved in regulation of acetyl-CoA biosynthetic process from pyruvate IMP
IMP: 通过突变表型推断
16606348 MGI
involved in regulation of bone resorption IMP
IMP: 通过突变表型推断
21803180 MGI
involved in regulation of cellular ketone metabolic process IMP
IMP: 通过突变表型推断
16606348 MGI
involved in regulation of fatty acid biosynthetic process IMP
IMP: 通过突变表型推断
19627255 MGI
involved in regulation of fatty acid oxidation IMP
IMP: 通过突变表型推断
16606348 MGI
involved in regulation of glucose metabolic process IMP
IMP: 通过突变表型推断
16606348 MGI
involved in regulation of pH IMP
IMP: 通过突变表型推断
22360721 MGI
involved in response to starvation IMP
IMP: 通过突变表型推断
16606348 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial

[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial

pyruvate dehydrogenase kinase 4

重组 Pdk4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P74639 PDK4 Protein, Mouse (sf9, His-GST) O70571 (M1-V412) ≥95%

相关产品

Pre-clinical Phase
生物活性分子 (13)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135954A PDK4-IN-1 hydrochloride 99.72% 否
HY-121744 PS10 Inhibitor 98.51% 否
HY-12492 VER-246608 Inhibitor 99.10% 否
HY-135954 PDK4-IN-1 99.34% 否
HY-114702 M77976 Inhibitor 99.44% 否
HY-139185 PROTAC ERRα Degrader-3 Inhibitor 98.82% 否
HY-134908 DHNA Inhibitor 99.65% 否
HY-116257 GSK-7227 Agonist / 否
HY-156109 PDK-IN-2 / 否
HY-157538 PDK4-IN-2 Inhibitor / 否
HY-RS10278 PDK4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16617 Pdk4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23052 Pdk4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pdk4 NCBI NCBI:5166
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