1. Gene
  2. Atf5 - activating transcription factor 5 Gene

Atf5 - activating transcription factor 5 Gene

种属: Rattus norvegicus

基因 ID: 282840 | 基因类型: protein coding

关于 Atf5

功能概要

Enables several functions, including DNA-binding transcription factor activity; chromatin binding activity; and heat shock protein binding activity. Involved in negative regulation of apoptotic process; negative regulation of astrocyte differentiation; and positive regulation of transcription, DNA-templated. Located in nucleus. Orthologous to human ATF5 (activating transcription factor 5). [provided by Alliance of Genome Resources, Apr 2022]

Atf5 基因产物(1)

mRNA Protein Name
NM_172336.4 NP_758839.3 cyclic AMP-dependent transcription factor ATF-5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
19531563 RGD
enables chromatin binding IDA
IDA: 通过直接分析推断
21212266 RGD
enables heat shock protein binding IPI
IPI: 通过物理相互作用推断
21521685 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
19531563 RGD
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
19531563 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
21212266 RGD
involved in negative regulation of astrocyte differentiation IMP
IMP: 通过突变表型推断
15829641 RGD
involved in negative regulation of neurogenesis IDA
IDA: 通过直接分析推断
12805299 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
19531563 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cyclic AMP-dependent transcription factor ATF-5

cAMP-dependent transcription factor ATF-5

transcription factor ATFx

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atf5 NCBI NCBI:22809