2. Gene
  3. KCNRG - potassium channel regulator Gene

KCNRG - potassium channel regulator Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：钾通道调节因子

种属: Homo sapiens

同用名: DLTET

基因 ID: 283518 | 基因类型: protein coding

关于 KCNRG

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:50,015,444-50,020,922 (from NCBI)

This gene has 2 transcripts (splice variants), 130 orthologues and 13 paralogues. Broad expression in testis (RPKM 38.4), bone marrow (RPKM 16.2) and 24 other tissues.

功能概要

该基因编码一种调节电压门控钾通道活性的蛋白质。该基因位于 13 号染色体上，与同一链上包含 13 的三联基序基因重叠。已发现该基因编码不同异构体的多个转录变体。[RefSeq 提供，2012 年 2 月]

This gene encodes a protein which regulates the activity of voltage-gated potassium channels. This gene is on chromosome 13 and overlaps the gene for tripartite motif containing 13 on the same strand. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

KCNRG 基因产物(2)

mRNA Protein Name
NM_173605.2 NP_775876.1 potassium channel regulatory protein isoform 1
NM_199464.3 NP_955751.1 potassium channel regulatory protein isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
19968958 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of delayed rectifier potassium channel activity IDA
IDA: 通过直接分析推断
19968958 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
19968958 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

KCNRG 蛋白结构

BTB_2

BTB_2: BTB/POZ domain (7 - 94)

  • 0
  • 100
  • 200
  • 272 a.a.
蛋白主名 其他名称

potassium channel regulatory protein

putative potassium channel regulatory protein

KCNRG 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
KCNRG Q8N5I3 FOSL1 Homo sapiens P15407
Anti Tag CoIP
33961781
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Y2H Pooling
16189514
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Y2H Pooling
19447967
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Validated Y2H
32296183
种属内
KCNRG Q8N5I3 metE Bacillus anthracis Q6KNA9
Y2H Pooling
20711500
种属内
KCNRG Q8N5I3 ROBO2 Homo sapiens Q9HCK4
Y2H
21900206
种属内
KCNRG Q8N5I3 ARHGDIA Homo sapiens P52565
Y2H
21900206
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Pull Down
16189514
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Y2H Prey Pooling
32296183
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Y2H Array
25416956
种属内
KCNRG Q8N5I3 KCNRG Homo sapiens Q8N5I3
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Autoimmune Polyendocrine Syndrome Type 1

Whitaker Syndrome

Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy

Autoimmune Polyglandular Syndrome I

Polyglandular Type I Autoimmune Syndrome
Autoimmune Polyendocrine Syndrome

Autoimmune Polyendocrinopathy

Autoimmune Polyglandular Failure

Autoimmune Polyglandular Syndrome

Polyendocrinopathies, Autoimmune

Lloyd'S Syndrome

Aps

Polyendocrinopathies Autoimmune

Polyendocrine Autoimmunity Syndrome

Lloyd Syndrome

Polyglandular Autoimmune Deficiency

Progressive Pluriglandular Insufficiency

Pluriglandular Autoimmune Atrophy

Pluriglandular Autoimmune Syndrome

Thyroid-Adrenocortical Insufficiency Syndrome
Chronic Mucocutaneous Candidiasis

Candidiasis, Chronic Mucocutaneous

Cmc

Candidiasis Chronic Mucocutaneous
Nail Disease

Nail Diseases

Abnormality Of The Nail

Nail Anomaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07178 KCNRG Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta KCNRG VGNC VGNC:73859
Rattus norvegicus KCNRG RGD RGD:1307199
Canis familiaris KCNRG VGNC VGNC:42292
Mus musculus KCNRG MGD MGI:2685591
Felis catus KCNRG VGNC VGNC:63046
Bos taurus KCNRG VGNC VGNC:30490
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