2. Gene
  3. SIGLEC15 - sialic acid binding Ig like lectin 15 Gene

SIGLEC15 - sialic acid binding Ig like lectin 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：唾液酸结合 Ig样凝集素 15

种属: Homo sapiens

同用名: CD33L3; HsT1361; SIGLEC-15

基因 ID: 284266 | 基因类型: protein coding

关于 SIGLEC15

Cytogenetic location: 18q12.3 Genomic coordinates (GRCh38): 18:45,825,675-45,844,094 (from NCBI)

This gene has 5 transcripts (splice variants), 181 orthologues and 16 paralogues. Biased expression in small intestine (RPKM 1.8), duodenum (RPKM 1.0) and 8 other tissues.

功能概要

预计参与肌动蛋白细胞骨架组织的调控；调节骨吸收；和破骨细胞发育的调节。预计是膜的组成部分。预计是含蛋白质复合物的一部分。预计在质膜上有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in regulation of actin Cytoskeleton organization; regulation of bone resorption; and regulation of osteoclast development. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SIGLEC15 基因产物(1)

mRNA Protein Name
NM_213602.3 NP_998767.1 sialic acid-binding Ig-like lectin 15 precursor

SIGLEC15 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (46 - 164)

Ig_2

Ig_2: Immunoglobulin domain (182 - 250)

  • 0
  • 100
  • 200
  • 300
  • 328 a.a.
蛋白主名 其他名称

sialic acid-binding Ig-like lectin 15

CD33 antigen-like 3

重组 SIGLEC15 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70738 Siglec-15 Protein, Human (HEK293, mFc) Q6ZMC9 (F20-T263) ≥95%
HY-P70742 Siglec-15 Protein, Human (HEK293, Fc) Q6ZMC9 (F20-T263) ≥95%
HY-P70767 Siglec-15 Protein, Human (Biotinylated, HEK293, Fc-Avi) Q6ZMC9 (F20-T263) ≥95%
HY-P72475 Siglec-15 Protein, Human (HEK293, His) Q6ZMC9 (F20-T263) ≥95%
HY-P78515 Siglec-15 Protein, Human (HEK293, His-Avi) Q6ZMC9 (F20-T263) ≥95%
HY-P78910 Siglec-15 Protein, Human (Biotinylated, HEK293, His-Avi) Q6ZMC9 (F20-T263) ≥95%

关联疾病

疾病名称 别名
Chromophobe Renal Cell Carcinoma

Chromophobe Adenocarcinoma

Chromophobe Carcinoma Of Kidney

Kidney Chromophobe

Renal Cell Carcinoma, Chromophobe Cell

Crcc

Chrcc

Chromophobe Renal Cell Adenocarcinoma

Chromophobe Renal Carcinoma

Chromophobe Carcinoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12902 SIGLEC15 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SIGLEC15 RGD RGD:1565948
Mus musculus SIGLEC15 MGD MGI:3646642
Bos taurus SIGLEC15 VGNC VGNC:34618
Felis catus SIGLEC15 VGNC VGNC:65142
Canis familiaris SIGLEC15 VGNC VGNC:46169
Macaca mulatta SIGLEC15 VGNC VGNC:77319
Macaca fascicularis SIGLEC15 NCBI
Others SIGLEC15 NCBI
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