1. Gene
  2. Krt14 - keratin 14 Gene

Krt14 - keratin 14 Gene

种属: Rattus norvegicus

同用名: Ka14; Krt1-14

基因 ID: 287701 | 基因类型: protein coding

关于 Krt14

功能概要

Predicted to enable keratin filament binding activity. Involved in epithelial cell differentiation; response to ionizing radiation; and response to zinc ion. Located in keratin filament. Biomarker of esophagus small cell carcinoma. Human ortholog(s) of this gene implicated in Naegeli-Franceschetti-Jadassohn syndrome; dermatopathia pigmentosa reticularis; and epidermolysis bullosa simplex. Orthologous to human KRT14 (keratin 14). [provided by Alliance of Genome Resources, Apr 2022]

Krt14 基因产物(1)

mRNA Protein Name
NM_001008751.2 NP_001008751.1 keratin, type I cytoskeletal 14
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in epithelial cell differentiation IDA
IDA: 通过直接分析推断
8950218 RGD
involved in response to ionizing radiation IEP
IEP: 通过表达模式推断
12793764 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
16140947 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in keratin filament IDA
IDA: 通过直接分析推断
8950218 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

keratin, type I cytoskeletal 14

CK-14

K14

cytokeratin-14

keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)

keratin 14, type I

keratin complex 1, acidic, gene 14

type I keratin Ka14

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Krt14 NCBI NCBI:3861