2. Gene
  3. Kiss1 - KiSS-1 metastasis-suppressor Gene

Kiss1 - KiSS-1 metastasis-suppressor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Eseptin

基因 ID: 289023 | 基因类型: protein coding

关于 Kiss1

功能概要

Enables Kisspeptin Receptor binding activity. Involved in several processes, including generation of ovulation cycle rhythm; positive regulation of cell communication; and positive regulation of cytosolic calcium ion concentration involved in Phospholipase C-activating G protein-coupled signaling pathway. Located in several cellular components, including apical plasma membrane; extracellular space; and neuronal cell body. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor). [provided by Alliance of Genome Resources, Apr 2022]

Kiss1 基因产物(2)

mRNA Protein Name
NM_001412625.1 NP_001399554.1 metastasis-suppressor KiSS-1 precursor
NM_181692.2 NP_859043.1 metastasis-suppressor KiSS-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables kisspeptin receptor binding IPI
IPI: 通过物理相互作用推断
11457843 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in generation of ovulation cycle rhythm IMP
IMP: 通过突变表型推断
15976058 RGD
involved in negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
11457843 RGD
involved in phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11457843 RGD
involved in positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
16222076 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
17532794 RGD
involved in positive regulation of growth hormone secretion IDA
IDA: 通过直接分析推断
17532794 RGD
involved in positive regulation of luteinizing hormone secretion IDA
IDA: 通过直接分析推断
17532794 RGD
involved in positive regulation of luteinizing hormone secretion IMP
IMP: 通过突变表型推断
17213691 RGD
NOT involved in positive regulation of stress-activated MAPK cascade IMP
IMP: 通过突变表型推断
16222076 RGD
involved in positive regulation of synaptic transmission IDA
IDA: 通过直接分析推断
16222076 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
17503086 RGD
located in extracellular space IDA
IDA: 通过直接分析推断
16339453 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
15976058 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metastasis-suppressor KiSS-1

Kiss1 variant E1a-E2b-E3

Kiss1 variant E1b-E2a-E3

Kiss1 variant E1b-E2b-E3

MLL septin-like fusion

kisspeptin-1

metastin

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P0076A TAK-448 acetate 99.70% Phase 2
HY-P0076 TAK-448 99.90% Phase 2
Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1022 Kisspeptin-54(human) 98.00% 否
HY-P1196A Kisspeptin 234 TFA Antagonist 98.92% 否
HY-P1197A Kisspeptin-10 (mouse, rat) (TFA) 99.57% 否
HY-P10489 Kisspeptin-14 human 99.84% 否
HY-P2161B TAK-683 acetate 99.91% 否
HY-P1022A Kisspeptin-54(human) TFA 98.86% 否
HY-P1196 Kisspeptin 234 Antagonist / 否
HY-P1197 Kisspeptin-10 (mouse, rat) 99.53% 否
HY-P2161 TAK-683 / 否
HY-P2161A TAK-683 TFA / 否
HY-P2191 KISS1-305 / 否
HY-RS07315 KISS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07316 KISS1R Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07317 Kiss1r Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07318 Kiss1r Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18527 Kiss1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25009 Kiss1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kiss1 NCBI NCBI:3814
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