2. Gene
  3. SLC43A3 - solute carrier family 43 member 3 Gene

SLC43A3 - solute carrier family 43 member 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 43 成员 3

种属: Homo sapiens

同用名: EEG1; ENBT1; FOAP-13; PRO1659; SEEEG-1

基因 ID: 29015 | 基因类型: protein coding

关于 SLC43A3

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,406,954-57,427,580 (from NCBI)

This gene has 26 transcripts (splice variants) and 282 orthologues. Ubiquitous expression in thyroid (RPKM 33.1), liver (RPKM 25.7) and 24 other tissues.

功能概要

预测启用跨膜转运蛋白活动。预计参与跨膜运输。预计是膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC43A3 基因产物(5)

mRNA Protein Name
NM_001278201.2 NP_001265130.1 equilibrative nucleobase transporter 1 isoform 1
NM_001278206.2 NP_001265135.1 equilibrative nucleobase transporter 1 isoform 2
NM_014096.4 NP_054815.2 equilibrative nucleobase transporter 1 isoform 1
NM_017611.3 NP_060081.1 equilibrative nucleobase transporter 1 isoform 1
NM_199329.3 NP_955361.1 equilibrative nucleobase transporter 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adenine transmembrane transporter activity IDA
IDA: 通过直接分析推断
26455426 GOA
enables guanine transmembrane transporter activity IDA
IDA: 通过直接分析推断
26455426 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
enables xenobiotic transmembrane transporter activity IDA
IDA: 通过直接分析推断
30910793 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in hypoxanthine transport IDA
IDA: 通过直接分析推断
26455426 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
26455426 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC43A3 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (65 - 439)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 491 a.a.
蛋白主名 其他名称

equilibrative nucleobase transporter 1

likely ortholog of mouse embryonic epithelial gene 1

SLC43A3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SLC43A3 Q8NBI5 VCP Homo sapiens P55072
Y2H Pooling
32814053
种属内
SLC43A3 Q8NBI5 VCP Homo sapiens P55072
Validated Y2H
32814053
种属内
SLC43A3 Q8NBI5 VCP Homo sapiens P55072
Y2H Array
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ovarian Angiosarcoma

Hemangiosarcoma Of Ovary
Thiamine-Responsive Megaloblastic Anemia Syndrome

TRMA

Rogers Syndrome

Thiamine-Responsive Myelodysplasia

Thiamine-Responsive Anemia Syndrome

Thiamine Metabolism Dysfunction Syndrome 1

Thmd1

Megaloblastic Anemia, Thiamine-Responsive, With Diabetes Mellitus And Sensorineural Deafness

Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Deafness

Thiamine Responsive Megaloblastic Anemia Syndrome

Megaloblastic Anemia Thiamine-Responsive With Diabetes Mellitus And Sensorineural Deafness

Thiamine-Responsive Megaloblastic Anemia

Thiamine-Responsive Anaemia Syndrome

Thiamine-Responsive Megaloblastic Anaemia Syndrome

Thiamine-Responsive Megaloblastic Anaemia With Diabetes Mellitus And Sensorineural Deafness

Thiamine-Responsive Megaloblastic Anemia With Diabetes Mellitus And Sensorineural Hearing Loss
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13250 SLC43A3 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC43A3 VGNC VGNC:54892
Mus musculus SLC43A3 MGD MGI:1931054
Canis familiaris SLC43A3 VGNC VGNC:49711
Felis catus SLC43A3 VGNC VGNC:81936
Macaca mulatta SLC43A3 VGNC VGNC:108151
Rattus norvegicus SLC43A3 RGD RGD:1312016
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