2. Gene
  3. Mstn - myostatin Gene

Mstn - myostatin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Gdf8

基因 ID: 29152 | 基因类型: protein coding

关于 Mstn

功能概要

This gene encodes a member of the TGF-beta (transforming growth factor-beta) family of proteins. The encoded preproprotein is proteolytically processed to generate an N-terminal propeptide and a C-terminal subunit. The C-terminal subunits form the mature homodimer, which negatively regulates skeletal muscle cell proliferation and differentiation. Mutations in this gene are associated with increased skeletal muscle mass in humans and Other mammals. [provided by RefSeq, Jun 2016]

Mstn 基因产物(1)

mRNA Protein Name
NM_019151.2 NP_062024.1 growth/differentiation factor 8 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hypoxia IEP
IEP: 通过表达模式推断
30765322 RGD
involved in negative regulation of muscle hypertrophy IMP
IMP: 通过突变表型推断
16810717 RGD
involved in negative regulation of skeletal muscle tissue growth IMP
IMP: 通过突变表型推断
16575154 RGD
involved in ovulation cycle process IEP
IEP: 通过表达模式推断
18845635 RGD
involved in response to electrical stimulus IEP
IEP: 通过表达模式推断
18787495 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
18845635 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
14749210 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
16919545 RGD
involved in response to gravity IEP
IEP: 通过表达模式推断
11115768 RGD
involved in response to muscle activity IEP
IEP: 通过表达模式推断
15743390 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
18841527 RGD
involved in skeletal muscle atrophy IEP
IEP: 通过表达模式推断
15758361 RGD
involved in skeletal muscle tissue regeneration IEP
IEP: 通过表达模式推断
11206133 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16575154 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

growth/differentiation factor 8

GDF-8

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08731 MSTN Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18142 Mstn Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24617 Mstn Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mstn NCBI NCBI:2660
Felis catus Mstn NCBI NCBI:101081322
Mus musculus Mstn NCBI NCBI:17700
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