2. Gene
  3. Arg1 - arginase 1 Gene

Arg1 - arginase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29221 | 基因类型: protein coding

关于 Arg1

功能概要

Enables Arginase activity; identical protein binding activity; and manganese ion binding activity. Involved in several processes, including cellular response to hormone stimulus; gland development; and response to vitamin. Located in several cellular components, including extracellular space; mitochondrial outer membrane; and neuronal cell body. Used to study acute necrotizing pancreatitis and hypertension. Biomarker of several diseases, including acute kidney failure; cholestasis; silicosis; ureteral obstruction; and uveitis. Human ortholog(s) of this gene implicated in asthma; hepatocellular carcinoma; and hyperargininemia. Orthologous to human ARG1 (Arginase 1). [provided by Alliance of Genome Resources, Apr 2022]

Arg1 基因产物(1)

mRNA Protein Name
NM_017134.3 NP_058830.2 arginase-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables arginase activity IDA
IDA: 通过直接分析推断
4062872 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
1569574 RGD
enables manganese ion binding IDA
IDA: 通过直接分析推断
12820884 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in arginine catabolic process to ornithine IDA
IDA: 通过直接分析推断
15753084 RGD
involved in arginine metabolic process IDA
IDA: 通过直接分析推断
4062872 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: 通过表达模式推断
11250887 RGD
involved in cellular response to glucagon stimulus IEP
IEP: 通过表达模式推断
8460937 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: 通过表达模式推断
18001708 RGD
involved in cellular response to interleukin-4 IEP
IEP: 通过表达模式推断
14618299 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
9013624 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
12069499 RGD
involved in collagen biosynthetic process IMP
IMP: 通过突变表型推断
20107769 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
7649538 RGD
involved in liver development IEP
IEP: 通过表达模式推断
8690412 RGD
involved in lung development IEP
IEP: 通过表达模式推断
18192591 RGD
involved in mammary gland involution IEP
IEP: 通过表达模式推断
20110414 RGD
involved in maternal process involved in female pregnancy IEP
IEP: 通过表达模式推断
16735458 RGD
involved in positive regulation of endothelial cell proliferation IDA
IDA: 通过直接分析推断
11742824 RGD
involved in regulation of L-arginine import across plasma membrane IDA
IDA: 通过直接分析推断
11120661 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
16459053 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
15458774 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
15735325 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
16570515 RGD
involved in response to herbicide IEP
IEP: 通过表达模式推断
20388547 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
9686345 RGD
involved in response to manganese ion IEP
IEP: 通过表达模式推断
15564441 RGD
involved in response to methylmercury IEP
IEP: 通过表达模式推断
18488197 RGD
involved in response to peptide hormone IEP
IEP: 通过表达模式推断
19386725 RGD
involved in response to selenium ion IEP
IEP: 通过表达模式推断
14624471 RGD
involved in response to steroid hormone IEP
IEP: 通过表达模式推断
9688877 RGD
involved in response to vitamin A IEP
IEP: 通过表达模式推断
18271400 RGD
involved in response to vitamin E IEP
IEP: 通过表达模式推断
14624471 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
15888029 RGD
involved in response to zinc ion IEP
IEP: 通过表达模式推断
11686772 RGD
involved in urea cycle IDA
IDA: 通过直接分析推断
4062872 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16872590 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
15753084 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
16914676 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

arginase-1

AI type I arginase

arginase, liver

liver-type arginase

type I arginase

相关产品

Pre-clinical Phase
生物活性分子 (22)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-145331A ARG1-IN-1 hydrochloride Inhibitor ≥90.0% 否
HY-103544 [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P 98.48% 否
HY-P1490 Bradykinin (2-9) Modulator 97.15% 否
HY-RS00907 ARG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-145331 ARG1-IN-1 Inhibitor / 否
HY-161061 Arginase inhibitor 7 Inhibitor / 否
HY-163426S AFFGHYLYEVAR-(Arg-13C6,15N4) / 否
HY-169859 EP4 receptor antagonist 7 Antagonist / 否
HY-N11451 Lacto-N-fucopentaose III Activator / 否
HY-P3225 (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P acetate Antagonist / 否
HY-P3880 (D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P Antagonist / 否
HY-P3881 (D-Arg1,D-Pro2,D-Phe7,D-His9)-Substance P Antagonist / 否
HY-P6421S LGPLVEQG-Arg(13C6,15N4) TFA / 否
HY-P6422S LAVYQAGA-Arg(13C6,15N4) TFA / 否
HY-P6423S CLAVYQAGA-Arg(13C6,15N4) TFA / 否
HY-P6424S LGADMEDVCG-Arg(13C6,15N4) TFA / 否
HY-RS14543 TINAGL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-173452 DT-23 Inhibitor / 否
HY-P6425S LCADMEDV-Arg(13C6,15N4) TFA / 否
HY-RS17033 Arg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18727 Tinagl1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23477 Arg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Arg1 NCBI NCBI:383
Mus musculus Arg1 NCBI NCBI:11846
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z