1. Immunology/Inflammation Metabolic Enzyme/Protease
  2. Arginase Aldehyde Dehydrogenase (ALDH) Indoleamine 2,3-Dioxygenase (IDO)
  3. Lacto-N-fucopentaose III

Lacto-N-fucopentaose III  (Synonyms: LNFP-III)

目录号: HY-N11451
产品使用指南

Lacto-N-fucopentaose III (LNFP-III) 是一种免疫调节剂。Lacto-N-fucopentaose III 可降低实验性自身免疫性脑脊髓炎 (EAE) 和中枢神经系统炎症的严重程度。

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Lacto-N-fucopentaose III Chemical Structure

Lacto-N-fucopentaose III Chemical Structure

CAS No. : 25541-09-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lacto-N-fucopentaose III (LNFP-III) is an immune modulator. Lacto-N-fucopentaose III reduces the severity of experimental autoimmune encephalomyelitis (EAE) and CNS inflammation[1].

体外研究
(In Vitro)

Lacto-N-fucopentaose III glycan (LNFP-III; 50 μg/mL; 48 h) 诱导炎症单核细胞产生一氧化氮。Lacto-N-fucopentaose III 减少树突状细胞跨脑内皮的迁移[1]
Lacto-N-fucopentaose III glycan (50 μg/mL; 48 h) 显著增加精氨酸酶 I (Aldh1a2)、醛脱氢酶 1、A2 亚家族 (Aldh1a2)、吲哚胺 2,3-双加氧酶 1 (Ido1) 和血红素加氧酶 1 (Homx1) mRNA的表达[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Lacto-N-fucopentaose III glycan (50 μg/mouse; i.v.; twice a week for 2 weeks) 显著降低实验性自身免疫性脑脊髓炎 (EAE) 和中枢神经系统炎症的严重程度,并扭曲小鼠对 Th2 显性谱的外周免疫反应[1]
Lacto-N-fucopentaose III (35 μg dextran conjugate/mouse; s.c.; daily for 2 weeks) 改善 Gulf War Illness 小鼠模型的急性和持续性海马突触可塑性和传递缺陷[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

853.77

Formula

C32H55NO25

CAS 号
结构分类
初始来源

schistosomula

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Lacto-N-fucopentaose III
目录号:
HY-N11451
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