2. Gene
  3. Sox10 - SRY-box transcription factor 10 Gene

Sox10 - SRY-box transcription factor 10 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29361 | 基因类型: protein coding

关于 Sox10

功能概要

Enables several functions, including DNA-binding transcription activator activity; promoter-specific chromatin binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to progesterone stimulus; regulation of gene expression; and regulation of nervous system development. Located in cytoplasm and nucleus. Colocalizes with chromatin. Human ortholog(s) of this gene implicated in Kallmann syndrome; PCWH syndrome; Waardenburg syndrome type 2E; and Waardenburg syndrome type 4C. Orthologous to human SOX10 (SRY-box transcription factor 10). [provided by Alliance of Genome Resources, Apr 2022]

Sox10 基因产物(1)

mRNA Protein Name
NM_019193.3 NP_062066.1 transcription factor SOX-10
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
9412504 RGD
enables DNA-binding transcription activator activity IDA
IDA: 通过直接分析推断
26525805 RGD
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
10559384 RGD
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
16582099 RGD
enables chromatin binding IDA
IDA: 通过直接分析推断
27466180 RGD
enables promoter-specific chromatin binding IMP
IMP: 通过突变表型推断
22037207 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16214168 RGD
enables transcription cis-regulatory region binding IDA
IDA: 通过直接分析推断
26525805 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to progesterone stimulus IEP
IEP: 通过表达模式推断
17478888 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
24403178 RGD
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
16582099 RGD
involved in negative regulation of Schwann cell proliferation IMP
IMP: 通过突变表型推断
25536222 RGD
involved in positive regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
16582099 RGD
involved in positive regulation of gene expression IMP
IMP: 通过突变表型推断
10559384 RGD
involved in positive regulation of myelination IMP
IMP: 通过突变表型推断
25536222 RGD
involved in regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
9412504 RGD
involved in stem cell differentiation IEP
IEP: 通过表达模式推断
12691661 RGD
involved in transcription elongation by RNA polymerase II IDA
IDA: 通过直接分析推断
25524031 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in chromatin IDA
IDA: 通过直接分析推断
27466180 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transcription factor SOX-10

SRY (sex determining region Y)-box 10

SRY box 10

SRY-box containing gene 10

Sox10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Sox10 O55170 NMI Homo sapiens Q13287
Confocal
16214168
种属间
Sox10 O55170 NMI Homo sapiens Q13287
Pull Down
16214168
种属间
Sox10 O55170 NMI Homo sapiens Q13287
Y2H
16214168
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13583 SOX10 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18684 Sox10 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25170 Sox10 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sox10 NCBI NCBI:6663
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z