2. Gene
  3. Por - cytochrome p450 oxidoreductase Gene

Por - cytochrome p450 oxidoreductase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: CYPOR

基因 ID: 29441 | 基因类型: protein coding

关于 Por

功能概要

Enables several functions, including iron-cytochrome-c reductase activity; nucleotide binding activity; and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Involved in several processes, including cellular response to hormone stimulus; negative regulation of hydrolase activity; and positive regulation of steroid biosynthetic process. Located in membrane and mitochondrion. Human ortholog(s) of this gene implicated in congenital adrenal hyperplasia and Cytochrome P450 oxidoreductase deficiency. Orthologous to human POR (Cytochrome P450 oxidoreductase). [provided by Alliance of Genome Resources, Apr 2022]

Por 基因产物(1)

mRNA Protein Name
NM_031576.2 NP_113764.1 NADPH--cytochrome P450 reductase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables FMN binding IMP
IMP: 通过突变表型推断
16928691 RGD
enables NADP binding IDA
IDA: 通过直接分析推断
9774150 RGD
enables NADP binding IMP
IMP: 通过突变表型推断
16928691 RGD
enables NADPH-hemoprotein reductase activity IDA
IDA: 通过直接分析推断
9774150 RGD
enables NADPH-hemoprotein reductase activity IMP
IMP: 通过突变表型推断
16928691 RGD
enables cytochrome-b5 reductase activity, acting on NAD(P)H IDA
IDA: 通过直接分析推断
16055078 RGD
enables electron transfer activity IDA
IDA: 通过直接分析推断
19171935 RGD
enables enzyme binding IDA
IDA: 通过直接分析推断
9774150 RGD
enables enzyme binding IMP
IMP: 通过突变表型推断
16928691 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
11350928 RGD
enables flavin adenine dinucleotide binding IMP
IMP: 通过突变表型推断
16928691 RGD
enables hydrolase activity IDA
IDA: 通过直接分析推断
16226717 RGD
enables iron-cytochrome-c reductase activity IDA
IDA: 通过直接分析推断
15823091 RGD
enables nitric oxide dioxygenase NAD(P)H activity IDA
IDA: 通过直接分析推断
19152507 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in carnitine metabolic process IEP
IEP: 通过表达模式推断
16616465 RGD
involved in cellular response to follicle-stimulating hormone stimulus IEP
IEP: 通过表达模式推断
19077323 RGD
involved in cellular response to gonadotropin stimulus IEP
IEP: 通过表达模式推断
19077323 RGD
involved in cellular response to peptide hormone stimulus IEP
IEP: 通过表达模式推断
19077323 RGD
involved in demethylation IDA
IDA: 通过直接分析推断
19171935 RGD
involved in fatty acid oxidation IDA
IDA: 通过直接分析推断
17400174 RGD
involved in flavonoid metabolic process IEP
IEP: 通过表达模式推断
18803703 RGD
involved in internal peptidyl-lysine acetylation IDA
IDA: 通过直接分析推断
18194664 RGD
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
19264869 RGD
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
IMP: 通过突变表型推断
19264869 RGD
involved in negative regulation of lipase activity IDA
IDA: 通过直接分析推断
18801337 RGD
involved in nitrate catabolic process IDA
IDA: 通过直接分析推断
16527817 RGD
involved in nitric oxide catabolic process IDA
IDA: 通过直接分析推断
19152507 RGD
involved in nitric oxide catabolic process IMP
IMP: 通过突变表型推断
19152507 RGD
involved in positive regulation of cholesterol biosynthetic process IMP
IMP: 通过突变表型推断
19264869 RGD
involved in positive regulation of chondrocyte differentiation IMP
IMP: 通过突变表型推断
19264869 RGD
involved in positive regulation of smoothened signaling pathway IMP
IMP: 通过突变表型推断
19264869 RGD
involved in positive regulation of steroid hormone biosynthetic process IDA
IDA: 通过直接分析推断
2495435 RGD
involved in regulation of cholesterol metabolic process IMP
IMP: 通过突变表型推断
19264869 RGD
involved in regulation of growth plate cartilage chondrocyte proliferation IMP
IMP: 通过突变表型推断
19264869 RGD
involved in response to dexamethasone IDA
IDA: 通过直接分析推断
27856527 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
17392395 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19265259 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

NADPH--cytochrome P450 reductase

CPR

P450 (cytochrome) oxidoreductase

P450R

cytochrome P450 reductase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P0083 Ornipressin Agonist 99.28% 否
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15630 VDAC2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS10880 POR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P0083A Ornipressin acetate Agonist 99.63% 否
HY-RS17068 Por Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23512 Por Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Por NCBI NCBI:5447
Macaca fascicularis Por NCBI
Mus musculus Por NCBI NCBI:18984
Macaca mulatta Por NCBI NCBI:715888
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