2. Gene
  3. Pde3b - phosphodiesterase 3B Gene

Pde3b - phosphodiesterase 3B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: RcGIPl; CGI PDE

基因 ID: 29516 | 基因类型: protein coding

关于 Pde3b

功能概要

Enables 3',5'-cyclic-AMP phosphodiesterase activity and phosphoprotein binding activity. Involved in negative regulation of cAMP-mediated signaling and negative regulation of Insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be part of guanyl-nucleotide exchange factor complex. Predicted to be active in membrane. Orthologous to human PDE3B (phosphodiesterase 3B). [provided by Alliance of Genome Resources, Apr 2022]

Pde3b 基因产物(1)

mRNA Protein Name
NM_017229.2 NP_058925.2 cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 3',5'-cyclic-AMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
9631240 RGD
enables 3',5'-cyclic-GMP phosphodiesterase activity IDA
IDA: 通过直接分析推断
9631240 RGD
enables phosphoprotein binding IDA
IDA: 通过直接分析推断
16225849 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of cAMP/PKA signal transduction IMP
IMP: 通过突变表型推断
9884079 RGD
involved in negative regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
18706893 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

cGMP-inhibited 3',5'-cyclic phosphodiesterase B

CGI-PDE B

CGIPDE1

cyclic GMP-inhibited phosphodiesterase B

phosphodiesterase 3B, cGMP-inhibited

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-U00186 K134 Inhibitor 99.84% Phase 2
HY-145924 BAY 2666605 Inhibitor 99.74% Phase 1
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-101312 Cilostamide Inhibitor 99.64% 否
HY-136350 BRD9500 Modulator 99.46% 否
HY-136350B (S)-BRD9500 Control 99.67% 否
HY-163285 PDE3B-IN-1 Inhibitor / 否
HY-168966 JNJ-54082730 / 否
HY-RS10219 PDE3B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18399 Pde3b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24880 Pde3b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde3b NCBI NCBI:5140
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