2. Gene
  3. Kcnq3 - potassium voltage-gated channel subfamily Q member 3 Gene

Kcnq3 - potassium voltage-gated channel subfamily Q member 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29682 | 基因类型: protein coding

关于 Kcnq3

功能概要

Enables several functions, including Calmodulin binding activity; enzyme binding activity; and transmembrane transporter binding activity. Involved in cellular response to ammonium ion; nervous system development; and potassium ion transmembrane transport. Located in several cellular components, including axon initial segment; membrane raft; and neuronal cell body. Is integral component of plasma membrane. Part of voltage-gated Potassium Channel complex. Human ortholog(s) of this gene implicated in autistic disorder and benign neonatal seizures. Orthologous to human KCNQ3 (potassium voltage-gated channel subfamily Q member 3). [provided by Alliance of Genome Resources, Apr 2022]

Kcnq3 基因产物(1)

mRNA Protein Name
NM_031597.5 NP_113785.4 potassium voltage-gated channel subfamily KQT member 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calmodulin binding IDA
IDA: 通过直接分析推断
24333508 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
15304482 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
24333508 RGD
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
17322297 RGD
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
9836639 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to ammonium ion IMP
IMP: 通过突变表型推断
24333508 RGD
involved in ganglion development IEP
IEP: 通过表达模式推断
12832524 RGD
involved in monoatomic ion transmembrane transport IMP
IMP: 通过突变表型推断
15304482 RGD
involved in oligodendrocyte development IEP
IEP: 通过表达模式推断
21750731 RGD
involved in potassium ion transmembrane transport IDA
IDA: 通过直接分析推断
9836639 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon initial segment IDA
IDA: 通过直接分析推断
24333508 RGD
located in cell surface IDA
IDA: 通过直接分析推断
15304482 RGD
located in dendrite IDA
IDA: 通过直接分析推断
24333508 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
12832524 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
9836639 RGD
located in somatodendritic compartment IDA
IDA: 通过直接分析推断
24333508 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
9836639 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium voltage-gated channel subfamily KQT member 3

KQT-like 3

potassium channel subunit alpha KvLQT3

potassium channel, voltage-gated KQT-like subfamily Q, member 3

potassium voltage-gated channel, KQT-like subfamily, member 3

voltage-gated potassium channel subunit Kv7.3

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-108577 XE991 dihydrochloride Inhibitor 99.63% 否
HY-122114 ICA-27243 Activator 99.27% 否
HY-108577A XE991 Inhibitor 99.69% 否
HY-130070 QO-40 Activator 98.77% 否
HY-RS07175 KCNQ3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19700 Kcnq3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26195 Kcnq3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnq3 NCBI NCBI:3786
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