2. Gene
  3. Prkar2a - protein kinase cAMP-dependent type II regulatory subunit alpha Gene

Prkar2a - protein kinase cAMP-dependent type II regulatory subunit alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 29699 | 基因类型: protein coding

关于 Prkar2a

功能概要

Enables several functions, including beta-2 Adrenergic Receptor binding activity; cAMP binding activity; and cAMP-dependent protein kinase regulator activity. Involved in regulation of protein kinase activity and response to clozapine. Located in T-tubule and perinuclear region of cytoplasm. Part of cAMP-dependent protein kinase complex. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Prkar2a 基因产物(1)

mRNA Protein Name
NM_019264.2 NP_062137.1 cAMP-dependent protein kinase type II-alpha regulatory subunit
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-2 adrenergic receptor binding IPI
IPI: 通过物理相互作用推断
20395454 RGD
enables cAMP binding IDA
IDA: 通过直接分析推断
11907174 RGD
enables cAMP-dependent protein kinase regulator activity IDA
IDA: 通过直接分析推断
11907174 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
17081990 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10618500 RGD
enables protein domain specific binding IDA
IDA: 通过直接分析推断
16306226 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
17081990 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
17081990 RGD
enables small molecule binding IDA
IDA: 通过直接分析推断
21177871 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of protein kinase activity IDA
IDA: 通过直接分析推断
11907174 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in T-tubule IDA
IDA: 通过直接分析推断
14569017 RGD
part of cAMP-dependent protein kinase complex IDA
IDA: 通过直接分析推断
11907174 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
18550536 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
17081990 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cAMP-dependent protein kinase type II-alpha regulatory subunit

protein kinase cAMP-dependent type 2 regulatory subunit alpha

protein kinase, cAMP dependent regulatory, type II alpha

protein kinase, cAMP-dependent, regulatory subunit type II alpha

protein kinase, cAMP-dependent, regulatory, type 2, alpha

Prkar2a 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Prkar2a P12368 PDE4DIP Homo sapiens Q5VU43-11
Anti Bait CoIP
21569246
种属间
Prkar2a P12368 PDE4DIP Homo sapiens Q5VU43-11
Anti Tag CoIP
21569246
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11114 PRKAR2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22020 Prkar2a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28538 Prkar2a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Prkar2a NCBI NCBI:5576
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