1. Gene
  2. Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene

Nmnat1 - nicotinamide nucleotide adenylyltransferase 1 Gene

种属: Rattus norvegicus

基因 ID: 298653 | 基因类型: protein coding

关于 Nmnat1

功能概要

Predicted to enable identical protein binding activity; nicotinamide-nucleotide adenylyltransferase activity; and nicotinate-nucleotide adenylyltransferase activity. Involved in negative regulation of apoptotic DNA fragmentation; negative regulation of neuron apoptotic process; and positive regulation of MAPK cascade. Located in cytoplasm and nucleus. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nmnat1 基因产物(1)

mRNA Protein Name
NM_001037556.2 NP_001032645.2 nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1
蛋白主名 其他名称

nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

nicotinamide mononucleotide adenylyl transferase 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nmnat1 NCBI NCBI:64802