2. Gene
  3. Pum2 - pumilio RNA-binding family member 2 Gene

Pum2 - pumilio RNA-binding family member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 298874 | 基因类型: protein coding

关于 Pum2

功能概要

Predicted to enable mRNA 3'-UTR binding activity and miRNA binding activity. Predicted to be involved in positive regulation of RIG-I signaling pathway; regulation of chromosome segregation; and regulation of gene expression. Predicted to act upstream of or within stress granule assembly. Predicted to be located in cytoplasmic stress granule; nuclear membrane; and perinuclear region of cytoplasm. Predicted to be active in cytosol. Orthologous to human PUM2 (pumilio RNA binding family member 2). [provided by Alliance of Genome Resources, Apr 2022]

Pum2 基因产物(1)

mRNA Protein Name
NM_001106715.1 NP_001100185.1 pumilio homolog 2
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression IMP
IMP: 通过突变表型推断
31606248 RGD
involved in positive regulation of sprouting of injured axon IMP
IMP: 通过突变表型推断
31606248 RGD
involved in regulation of intracellular mRNA localization IMP
IMP: 通过突变表型推断
31606248 RGD
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
20133610 RGD
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
20133610 RGD
involved in regulation of translation IMP
IMP: 通过突变表型推断
31606248 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
16775137 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
31606248 RGD
is active in postsynapse IDA
IDA: 通过直接分析推断
16775137 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pumilio homolog 2

pumilio 2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11462 PUM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22291 Pum2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28814 Pum2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pum2 NCBI NCBI:23369
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