1. Gene
  2. Sp7 - Sp7 transcription factor Gene

Sp7 - Sp7 transcription factor Gene

种属: Rattus norvegicus

同用名: Osx

基因 ID: 300260 | 基因类型: protein coding

关于 Sp7

功能概要

Predicted to enable DEAD/H-box RNA helicase binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hematopoietic stem cell differentiation; positive regulation of stem cell differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within osteoblast differentiation. Predicted to be located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 12. Orthologous to human SP7 (Sp7 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Sp7 基因产物(2)

mRNA Protein Name
NM_001037632.1 NP_001032721.1 transcription factor Sp7 isoform 1
NM_181374.2 NP_852039.2 transcription factor Sp7 isoform 2
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to zinc ion starvation IEP
IEP: 通过表达模式推断
21893222 RGD
involved in response to insulin IEP
IEP: 通过表达模式推断
20818503 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
20818503 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transcription factor Sp7

osterix

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sp7 NCBI NCBI:121340
Mus musculus Sp7 NCBI NCBI:170574