2. Gene
  3. Spdef - SAM pointed domain containing ets transcription factor Gene

Spdef - SAM pointed domain containing ets transcription factor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Pse; PDEF

基因 ID: 30051 | 基因类型: protein coding

关于 Spdef

功能概要

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Acts upstream of or within several processes, including columnar/cuboidal epithelial cell differentiation; positive regulation of cell fate commitment; and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human SPDEF (SAM pointed domain containing ETS transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Spdef 基因产物(4)

mRNA Protein Name
NM_001357728.1 NP_001344657.1 SAM pointed domain-containing Ets transcription factor
NM_001414277.1 NP_001401206.1 SAM pointed domain-containing Ets transcription factor
NM_001414278.1 NP_001401207.1 SAM pointed domain-containing Ets transcription factor
NM_013891.4 NP_038919.1 SAM pointed domain-containing Ets transcription factor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cell fate commitment IMP
IMP: 通过突变表型推断
19759516 MGI
acts upstream of epithelial cell fate commitment IMP
IMP: 通过突变表型推断
19759516 MGI
acts upstream of or within glandular epithelial cell development IMP
IMP: 通过突变表型推断
19549527 MGI
acts upstream of or within intestinal epithelial cell development IMP
IMP: 通过突变表型推断
19549527 MGI
acts upstream of or within lung goblet cell differentiation IDA
IDA: 通过直接分析推断
17347682 MGI
acts upstream of or within negative regulation of cell fate commitment IMP
IMP: 通过突变表型推断
19759516 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19759516 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19549527 MGI
acts upstream of or within positive regulation of cell fate commitment IMP
IMP: 通过突变表型推断
19759516 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
17347682 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17347682 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19549527 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19759516 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
19759516 MGI
acts upstream of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19549527 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17347682 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

SAM pointed domain-containing Ets transcription factor

prostate epithelium-specific Ets transcription factor

prostate specific ets transcription factor

prostate-derived Ets factor

prostate-specific Ets

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-B0603 Fluticasone Agonist 98.70% 是
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13652 SPDEF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17775 Spdef Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24242 Spdef Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spdef NCBI NCBI:25803
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