2. Gene
  3. Trem2 - triggering receptor expressed on myeloid cells 2 Gene

Trem2 - triggering receptor expressed on myeloid cells 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Trem2-Mia; Trem2-Mib

基因 ID: 301227 | 基因类型: protein coding

关于 Trem2

功能概要

Predicted to enable several functions, including amyloid-beta binding activity; lipoprotein particle binding activity; and phospholipid binding activity. Involved in cellular response to glucose stimulus and cellular response to hypoxia. Predicted to be located in plasma membrane raft. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Orthologous to human TREM2 (triggering receptor expressed on myeloid cells 2). [provided by Alliance of Genome Resources, Apr 2022]

Trem2 基因产物(1)

mRNA Protein Name
NM_001106884.1 NP_001100354.1 triggering receptor expressed on myeloid cells 2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
31900229 RGD
involved in cellular response to hypoxia IMP
IMP: 通过突变表型推断
31900229 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

triggering receptor expressed on myeloid cells 2

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-W017540 Cyclocreatine Activator 99.78% Phase 1
抗体抑制剂 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P991220 AL002 Agonist 98.01% Phase 2
HY-P990651 PY314 96.35% Phase 1
Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148095 TREM2 agonist-2 Agonist 99.93% 否
HY-160421 TREM2-IN-1 Inducer 99.34% 否
HY-RS15003 TREM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16526 Trem2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-169859 EP4 receptor antagonist 7 Antagonist / 否
HY-174369 TREM2 agonist-3 / 否
HY-174378 TREM2 agonist-4 Inhibitor / 否
HY-P10220 NOTA-COG1410 / 否
HY-W010270A Aurothiomalate disodium / 否
HY-W017540S Cyclocreatine-13C3 / 否
HY-RS22957 Trem2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990043 Iluzanebart 98.63% 否
HY-P991621 EOS006215 Inhibitor / 否
HY-P991174 Anti-TREM2 Antibody (AL2p-58) Inhibitor 97.43% 否
HY-P991442 DNL-919 Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trem2 NCBI NCBI:54209
Macaca fascicularis Trem2 NCBI NCBI:102133279
Mus musculus Trem2 NCBI NCBI:83433
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