2. Gene
  3. Trem1 - triggering receptor expressed on myeloid cells 1 Gene

Trem1 - triggering receptor expressed on myeloid cells 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 301229 | 基因类型: protein coding

关于 Trem1

功能概要

Predicted to enable scaffold protein binding activity. Involved in several processes, including cellular response to lipid; positive regulation of cardiac muscle cell apoptotic process; and positive regulation of macrophage chemotaxis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Used to study several diseases, including acute pancreatitis; Bacterial sepsis; mesenteric vascular occlusion; middle cerebral artery infarction; and pleural empyema. Biomarker of congestive heart failure; mental depression; periodontitis; and rheumatoid arthritis. Human ortholog(s) of this gene implicated in Bacterial sepsis and malaria. Orthologous to human TREM1 (triggering receptor expressed on myeloid cells 1). [provided by Alliance of Genome Resources, Apr 2022]

Trem1 基因产物(1)

mRNA Protein Name
NM_001106885.1 NP_001100355.1 triggering receptor expressed on myeloid cells 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
26383906 RGD
involved in cellular response to vitamin D IEP
IEP: 通过表达模式推断
29331667 RGD
involved in positive regulation of cell-matrix adhesion IDA
IDA: 通过直接分析推断
29331667 RGD
involved in positive regulation of cell-matrix adhesion IMP
IMP: 通过突变表型推断
29331667 RGD
involved in positive regulation of macrophage chemotaxis IDA
IDA: 通过直接分析推断
29331667 RGD
involved in positive regulation of macrophage chemotaxis IMP
IMP: 通过突变表型推断
29331667 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

triggering receptor expressed on myeloid cells 1

相关产品

Clinical Phase
生物活性分子 (2)
目录号 产品名 作用方式
纯度 Phase
HY-P3211A Nangibotide TFA Inhibitor 99.86% Phase 2
HY-P3211 Nangibotide Inhibitor 98.27% Phase 2
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-157122 VJDT Inhibitor 99.68% 否
HY-174369 TREM2 agonist-3 99.39% 否
HY-P10938 LP17 (human) Inhibitor 90.14% 否
HY-RS15002 TREM1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16560 Trem1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10088 Mouse TREM-1 SCHOOL peptide, control Control / 否
HY-P11077 LQEEDAGEYGCMVDGAR Inhibitor / 否
HY-RS22992 Trem1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Trem1 NCBI NCBI:54210
Mus musculus Trem1 NCBI NCBI:58217
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