2. Gene
  3. Pla2g7 - phospholipase A2 group VII Gene

Pla2g7 - phospholipase A2 group VII Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 301265 | 基因类型: protein coding

关于 Pla2g7

功能概要

Predicted to enable 1-alkyl-2-acetylglycerophosphocholine esterase activity; calcium-independent Phospholipase A2 activity; and phospholipid binding activity. Predicted to be involved in several processes, including glycerophospholipid catabolic process; plasma lipoprotein particle remodeling; and positive regulation of monocyte chemotaxis. Located in cytoplasm and extracellular space. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); glomerulonephritis (multiple); hemolytic-uremic syndrome; proteinuria (multiple); and type 2 diabetes mellitus. Orthologous to human PLA2G7 (Phospholipase A2 group VII). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g7 基因产物(1)

mRNA Protein Name
NM_001009353.1 NP_001009353.1 platelet-activating factor acetylhydrolase precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
8692015 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

platelet-activating factor acetylhydrolase

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-18540 KT109 Inhibitor 99.86% 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10634 PLA2G7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16659 Pla2g7 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23094 Pla2g7 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pla2g7 NCBI NCBI:7941
Mus musculus Pla2g7 NCBI NCBI:27226
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