1. Gene
  2. Top3a - DNA topoisomerase III alpha Gene

Top3a - DNA topoisomerase III alpha Gene

种属: Rattus norvegicus

基因 ID: 303194 | 基因类型: protein coding

关于 Top3a

功能概要

Predicted to enable DNA Topoisomerase type I (single strand cut, ATP-independent) activity and single-stranded DNA binding activity. Predicted to be involved in DNA topological change; chromosome separation; and mitochondrial DNA metabolic process. Predicted to be located in PML body. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 5. Orthologous to human TOP3A (DNA Topoisomerase III alpha). [provided by Alliance of Genome Resources, Apr 2022]

Top3a 基因产物(3)

mRNA Protein Name
XM_039087263.1 XP_038943191.1 DNA topoisomerase 3-alpha isoform X1
XM_039087264.1 XP_038943192.1 DNA topoisomerase 3-alpha isoform X2
XM_039087265.1 XP_038943193.1 DNA topoisomerase 3-alpha isoform X3
蛋白主名 其他名称

DNA topoisomerase 3-alpha

topoisomerase (DNA) III alpha

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Top3a NCBI NCBI:7156