Nbr1 - NBR1, autophagy cargo receptor Gene

种属: Rattus norvegicus

同用名: Ca125; RGD1311421

关于 Nbr1

功能概要

Predicted to enable mitogen-activated protein kinase binding activity and ubiquitin binding activity. Predicted to be involved in several processes, including negative regulation of osteoblast differentiation; regulation of bone mineralization; and regulation of stress-activated MAPK cascade. Predicted to be located in several cellular components, including late endosome; mitochondrial intermembrane space; and nuclear body. Predicted to be part of receptor complex. Predicted to be active in phagophore assembly site. Predicted to colocalize with autophagosome and mitochondrion. Orthologous to human NBR1 (NBR1 Autophagy cargo receptor). [provided by Alliance of Genome Resources, Apr 2022]