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  2. Tpr - translocated promoter region, nuclear basket protein Gene

Tpr - translocated promoter region, nuclear basket protein Gene

种属: Rattus norvegicus

基因 ID: 304862 | 基因类型: protein coding

关于 Tpr

功能概要

Predicted to enable several functions, including dynein complex binding activity; mitogen-activated protein kinase binding activity; and protein homodimerization activity. Predicted to be a structural constituent of nuclear pore. Involved in positive regulation of protein export from nucleus and protein export from nucleus. Located in nuclear inclusion body; nuclear membrane; and nuclear periphery. Part of nuclear pore nuclear basket. Orthologous to human TPR (translocated promoter region, nuclear basket protein). [provided by Alliance of Genome Resources, Apr 2022]

Tpr 基因产物(1)

mRNA Protein Name
NM_001107185.1 NP_001100655.2 nucleoprotein TPR
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
NOT involved in nuclear pore complex assembly IMP
IMP: 通过突变表型推断
11839768 RGD
involved in positive regulation of protein export from nucleus IMP
IMP: 通过突变表型推断
11839768 RGD
involved in protein export from nucleus IMP
IMP: 通过突变表型推断
11839768 RGD
NOT involved in regulation of protein import into nucleus IMP
IMP: 通过突变表型推断
11839768 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nuclear inclusion body IDA
IDA: 通过直接分析推断
11839768 RGD
located in nuclear membrane IDA
IDA: 通过直接分析推断
11839768 RGD
located in nuclear periphery IDA
IDA: 通过直接分析推断
11839768 RGD
part of nuclear pore nuclear basket IDA
IDA: 通过直接分析推断
11839768 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

nucleoprotein TPR

NPC-associated intranuclear protein

megator

translocated promoter region (to activated MET oncogene)

translocated promoter region protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tpr NCBI NCBI:7175
Mus musculus Tpr NCBI NCBI:108989