HDGF - heparin binding growth factor Gene

中文名称：肝素结合生长因子

种属: Homo sapiens

同用名: HMG1L2

基因 ID: 3068 | 基因类型: protein coding

关于 HDGF

Cytogenetic location: 1q23.1 Genomic coordinates (GRCh38): 1:156,742,107-156,767,366 (from NCBI)

This gene has 10 transcripts (splice variants), 188 orthologues and 4 paralogues. Ubiquitous expression in bone marrow (RPKM 90.4), liver (RPKM 48.1) and 25 other tissues.

功能概要

该基因编码肝细胞瘤衍生生长因子家族的一个成员。编码的蛋白质具有促有丝分裂和 DNA 结合活性，可能在细胞增殖和分化中发挥作用。该基因的高水平表达促进了许多肿瘤的生长。该基因最初被认为位于 X 染色体上；然而，该位置已被确定为对应于相关的假基因。已经描述了编码不同同种型的选择性剪接转录物变体。[RefSeq 提供，2016 年 1 月]

This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. High levels of expression of this gene enhance the growth of many tumors. This gene was thought initially to be located on chromosome X; however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2016]

HDGF 基因产物(6)

mRNA	Protein	Name
NM_001126050.2	NP_001119522.1	hepatoma-derived growth factor isoform b
NM_001126051.1	NP_001119523.1	hepatoma-derived growth factor isoform c
NM_001319186.2	NP_001306115.1	hepatoma-derived growth factor isoform d
NM_001319187.2	NP_001306116.1	hepatoma-derived growth factor isoform e
NM_001319188.2	NP_001306117.1	hepatoma-derived growth factor isoform e
NM_004494.3	NP_004485.1	hepatoma-derived growth factor isoform a

HDGF 蛋白结构

PWWP

0
100
200
240 a.a.

蛋白主名

其他名称

hepatoma-derived growth factor

epididymis secretory sperm binding protein

重组 HDGF 蛋白

目录号	产品名	蛋白编号	纯度
HY-P70368	HDGF Protein, Human (His)	P51858 (M1-Y100)	≥95%
HY-P700087AF	Animal-Free HDGF Protein, Human (His)	P51858 (M1-L240)	≥95%

关联疾病

疾病名称

别名

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06094	HDGF Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	HDGF	RGD	RGD:70961
Canis familiaris	HDGF	VGNC	VGNC:41627
Mus musculus	HDGF	MGD	MGI:1194494
Felis catus	HDGF	VGNC	VGNC:103733
Macaca mulatta	HDGF	VGNC	VGNC:99967
Bos taurus	HDGF	VGNC	VGNC:29787
Others	HDGF	NCBI

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)	站点地图隐私声明
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.	沪ICP备15051369号-4

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。沪(浦)应急管危经许[2021]201709(QFYS)

站点地图隐私声明

HDGF - heparin binding growth factor Gene

关于 HDGF

功能概要

HDGF 基因产物(6)

HDGF 蛋白结构

重组 HDGF 蛋白

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

HDGF - heparin binding growth factor Gene

关于 HDGF

功能概要

HDGF 基因产物(6)

HDGF 蛋白结构

重组 HDGF 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z