Blm - BLM RecQ like helicase Gene

种属: Rattus norvegicus

关于 Blm

功能概要

Predicted to enable several functions, including ATP binding activity; DNA binding activity; and DNA helicase activity. Predicted to be involved in several processes, including DNA geometric change; DNA metabolic process; and regulation of cellular macromolecule biosynthetic process. Predicted to act upstream of or within several processes, including negative regulation of thymocyte apoptotic process; regulation of DNA recombination; and replication-born double-strand break repair via sister chromatid exchange. Predicted to be located in cytosol; nucleus; and replication fork. Predicted to be part of protein-containing complex. Predicted to be active in chromosome; cytoplasm; and nucleus. Predicted to colocalize with PML body and chromosome, telomeric region. Human ortholog(s) of this gene implicated in Bloom syndrome. Orthologous to human BLM (BLM RecQ like helicase). [provided by Alliance of Genome Resources, Apr 2022]