Pde8a - phosphodiesterase 8A Gene

中文名称：磷酸二酯酶 8A

种属: Rattus norvegicus

同用名: RNPDE8A

关于 Pde8a

功能概要

预测该基因编码的蛋白编码的蛋白可启动 3',5'-cyclic-AMP 磷酸二酯酶活性； 3',5'-cyclic-GMP 磷酸二酯酶活性；和激酶结合活性。预计参与多个过程，包括细胞对表皮生长因子刺激的反应；过氧化氢诱导的细胞死亡的负调节； ERK1 和 ERK2 级联的正调控。与人 PDE8A（磷酸二酯酶 8A）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity; and kinase binding activity. Predicted to be involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of hydrogen peroxide-induced cell death; and positive regulation of ERK1 and ERK2 cascade. Orthologous to human PDE8A (phosphodiesterase 8A). [provided by Alliance of Genome Resources, Apr 2022]