2. Gene
  3. Hjv - hemojuvelin BMP co-receptor Gene

Hjv - hemojuvelin BMP co-receptor Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Hfe2; Rgmc

基因 ID: 310681 | 基因类型: protein coding

关于 Hjv

功能概要

Predicted to enable BMP binding activity; coreceptor activity; and Transferrin Receptor binding activity. Predicted to contribute to BMP Receptor activity. Predicted to be involved in several processes, including cellular iron ion homeostasis; protein autoprocessing; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within iron ion homeostasis; negative regulation of BMP signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in basolateral plasma membrane. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 2A. Orthologous to human HJV (hemojuvelin BMP co-receptor). [provided by Alliance of Genome Resources, Apr 2022]

Hjv 基因产物(1)

mRNA Protein Name
NM_001012080.2 NP_001012080.1 hemojuvelin precursor
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
16932966 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hemojuvelin

RGM domain family member C

hemochromatosis type 2 (juvenile) (human homolog)

hemochromatosis type 2 protein homolog

hemojuvelin BMP coreceptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06191 HJV Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18590 Hjv Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25075 Hjv Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991637 REGN7999 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hjv NCBI NCBI:148738
Macaca fascicularis Hjv NCBI NCBI:102138915
Mus musculus Hjv NCBI NCBI:69585
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