Gpr68 - G protein-coupled receptor 68 Gene

中文名称：G 蛋白偶联受体 68

种属: Rattus norvegicus

关于 Gpr68

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。预计参与细胞对 pH 值的反应。预计在单核细胞分化的负调节上游或负调节内起作用；参与细胞对葡萄糖刺激反应的胰岛素分泌的正调节；和破骨细胞发育的积极调节。预计是膜的组成部分。该基因的人类直系同源物与 2A6 型釉质发育不全症有关。与人 GPR68（G 蛋白偶联受体 68）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cellular response to pH. Predicted to act upstream of or within negative regulation of monocyte differentiation; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and positive regulation of osteoclast development. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A6. Orthologous to human GPR68 (G protein-coupled receptor 68). [provided by Alliance of Genome Resources, Apr 2022]