2. Gene
  3. Elk1 - ETS transcription factor ELK1 Gene

Elk1 - ETS transcription factor ELK1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 314436 | 基因类型: protein coding

关于 Elk1

功能概要

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-Fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Multiple isoforms are produced from this gene by the use of alternative translational start codons. [provided by RefSeq, Mar 2012]

Elk1 基因产物(1)

mRNA Protein Name
NM_001108059.3 NP_001101529.1 ETS domain-containing protein Elk-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
11557580 RGD
enables chromatin binding IDA
IDA: 通过直接分析推断
18768922 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
11557580 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to gamma radiation IDA
IDA: 通过直接分析推断
17949253 RGD
involved in cellular response to lipid IDA
IDA: 通过直接分析推断
18768922 RGD
involved in cellular response to testosterone stimulus IEP
IEP: 通过表达模式推断
14766003 RGD
involved in hippocampal neuron apoptotic process IMP
IMP: 通过突变表型推断
16549787 RGD
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
19029245 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
18322102 RGD
involved in response to fibroblast growth factor IDA
IDA: 通过直接分析推断
17156131 RGD
involved in response to light stimulus IDA
IDA: 通过直接分析推断
10383826 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon terminus IDA
IDA: 通过直接分析推断
9412502 RGD
located in dendrite IDA
IDA: 通过直接分析推断
16549787 RGD
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
16549787 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
16549787 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ETS domain-containing protein Elk-1

ELK1, ETS transcription factor

ELK1, member of ETS oncogene family

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-152860 Darizmetinib 99.94% 否
HY-135699 TD52 95.0% 否
HY-113592 ERK-IN-4 Inhibitor 99.61% 否
HY-135699A TD52 dihydrochloride 99.55% 否
HY-RS04305 ELK1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-111000 BNC-1 / 否
HY-163323 AKR1C3-IN-12 Inhibitor / 否
HY-RS07131 KCNH8 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-122241 MT477 Inhibitor / 否
HY-RS17329 Elk1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21611 Kcnh8 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23784 Elk1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Elk1 NCBI NCBI:2002
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