2. Gene
  3. Atf1 - activating transcription factor 1 Gene

Atf1 - activating transcription factor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Atf-1

基因 ID: 315305 | 基因类型: protein coding

关于 Atf1

功能概要

Enables DNA-binding transcription factor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in several processes, including positive regulation of macromolecule biosynthetic process; positive regulation of neuron projection development; and response to cobalt ion. Located in nucleus. Part of transcription regulator complex. Biomarker of polycystic kidney disease. Orthologous to human ATF1 (activating transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Atf1 基因产物(1)

mRNA Protein Name
NM_001100895.1 NP_001094365.1 cyclic AMP-dependent transcription factor ATF-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
14576830 RGD
enables protein-containing complex binding IDA
IDA: 通过直接分析推断
16373341 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
9489722 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15084519 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA replication IMP
IMP: 通过突变表型推断
11925444 RGD
involved in positive regulation of neuron projection development IMP
IMP: 通过突变表型推断
9489722 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
17822438 RGD
involved in protein-containing complex assembly IMP
IMP: 通过突变表型推断
10770487 RGD
involved in response to cobalt ion IEP
IEP: 通过表达模式推断
10559391 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
10683356 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of transcription regulator complex IDA
IDA: 通过直接分析推断
14576830 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cyclic AMP-dependent transcription factor ATF-1

相关产品

Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103100 SB-699551 99.53% 否
HY-108618 BC11-38 Inhibitor 99.42% 否
HY-N12887 Mycothiazole Inhibitor / 否
HY-RS01127 ATF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS05361 GDNF Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18337 Atf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24816 Atf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atf1 NCBI NCBI:466
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