2. Gene
  3. Tigar - Trp53 induced glycolysis regulatory phosphatase Gene

Tigar - Trp53 induced glycolysis regulatory phosphatase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 9630033F20Rik

基因 ID: 319801 | 基因类型: protein coding

关于 Tigar

功能概要

Enables fructose-2,6-bisphosphate 2-phosphatase activity. Involved in negative regulation of neuron death and response to ischemia. Acts upstream of or within several processes, including fructose 2,6-bisphosphate metabolic process; negative regulation of catabolic process; and positive regulation of cardiac muscle cell apoptotic process. Located in mitochondrion. Is expressed in brain; immune system; and liver. Orthologous to human TIGAR (TP53 induced glycolysis regulatory Phosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Tigar 基因产物(1)

mRNA Protein Name
NM_177003.5 NP_795977.1 fructose-2,6-bisphosphatase TIGAR
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables fructose-2,6-bisphosphate 2-phosphatase activity IMP
IMP: 通过突变表型推断
20935145 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
22044588 MGI
acts upstream of or within fructose 2,6-bisphosphate metabolic process IMP
IMP: 通过突变表型推断
20935145 MGI
acts upstream of glucose catabolic process to lactate via pyruvate IMP
IMP: 通过突变表型推断
20935145 MGI
acts upstream of glycolytic process IDA
IDA: 通过直接分析推断
20935145 MGI
acts upstream of or within intestinal epithelial cell development IMP
IMP: 通过突变表型推断
23726973 MGI
acts upstream of mitophagy IMP
IMP: 通过突变表型推断
22044588 MGI
acts upstream of or within negative regulation of glucose catabolic process to lactate via pyruvate IMP
IMP: 通过突变表型推断
20935145 MGI
acts upstream of or within negative regulation of glycolytic process IDA
IDA: 通过直接分析推断
20935145 MGI
acts upstream of or within negative regulation of mitophagy IMP
IMP: 通过突变表型推断
22044588 MGI
acts upstream of or within negative regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
22044588 MGI
acts upstream of or within positive regulation of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
22044588 MGI
involved in positive regulation of pentose-phosphate shunt IDA
IDA: 通过直接分析推断
24872551 MGI
acts upstream of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
22044588 MGI
acts upstream of or within response to gamma radiation IMP
IMP: 通过突变表型推断
23726973 MGI
involved in response to ischemia IDA
IDA: 通过直接分析推断
24872551 MGI
acts upstream of or within response to xenobiotic stimulus IMP
IMP: 通过突变表型推断
23726973 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
24872551 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
24872551 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fructose-2,6-bisphosphatase TIGAR

TP53-induced glycolysis and apoptosis regulator

TP53-induced glycolysis regulatory phosphatase

Trp53 induced glycolysis repulatory phosphatase

probable fructose-2,6-bisphosphatase TIGAR

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1925A GO-203 TFA 99.28% 否
HY-RS14523 TIGAR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18552 Tigar Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25034 Tigar Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tigar NCBI NCBI:57103
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