1. Gene
  2. Tnn - tenascin N Gene

Tnn - tenascin N Gene

种属: Mus musculus

同用名: Tnw; TN-W; tenascin-W

基因 ID: 329278 | 基因类型: protein coding

关于 Tnn

功能概要

Enables identical protein binding activity and Integrin binding activity. Involved in several processes, including generation of neurons; negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation; and negative regulation of osteoblast differentiation. Acts upstream of or within axonogenesis and cell-matrix adhesion. Located in several cellular components, including CA3 pyramidal cell dendrite; hippocampal mossy fiber expansion; and neuronal cell body. Is expressed in several structures, including forelimb pre-cartilage condensation; metanephros; palatal shelf; skeleton; and spleen. Orthologous to human TNN (tenascin N). [provided by Alliance of Genome Resources, Apr 2022]

Tnn 基因产物(1)

mRNA Protein Name
NM_177839.3 NP_808507.2 tenascin-N precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
14709716 MGI
enables integrin binding IDA
IDA: 通过直接分析推断
14709716 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axonogenesis IDA
IDA: 通过直接分析推断
12812753 MGI
acts upstream of or within cell-matrix adhesion IDA
IDA: 通过直接分析推断
14531729 MGI
involved in dendrite self-avoidance IDA
IDA: 通过直接分析推断
12812753 MGI
involved in negative regulation of canonical Wnt signaling pathway IDA
IDA: 通过直接分析推断
17395156 MGI
involved in negative regulation of neuron migration IDA
IDA: 通过直接分析推断
12812753 MGI
involved in negative regulation of osteoblast differentiation IDA
IDA: 通过直接分析推断
17395156 MGI
involved in negative regulation of osteoblast proliferation IDA
IDA: 通过直接分析推断
17395156 MGI
involved in neuron migration IDA
IDA: 通过直接分析推断
12812753 MGI
involved in neuron projection extension IDA
IDA: 通过直接分析推断
12812753 MGI
involved in osteoblast development IDA
IDA: 通过直接分析推断
17395156 MGI
involved in positive regulation of neuron projection development IDA
IDA: 通过直接分析推断
12812753 MGI
involved in regulation of bone development IDA
IDA: 通过直接分析推断
17395156 MGI
involved in regulation of cell adhesion IDA
IDA: 通过直接分析推断
14709716 MGI
involved in regulation of cell migration IDA
IDA: 通过直接分析推断
14709716 MGI
involved in regulation of smooth muscle tissue development IDA
IDA: 通过直接分析推断
14709716 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in CA3 pyramidal cell dendrite IDA
IDA: 通过直接分析推断
12812753 MGI
located in cell surface IDA
IDA: 通过直接分析推断
12812753 MGI
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
14709716 MGI
located in extracellular matrix IDA
IDA: 通过直接分析推断
14709716 MGI
located in hippocampal mossy fiber expansion IDA
IDA: 通过直接分析推断
12812753 MGI
located in neuron projection IDA
IDA: 通过直接分析推断
12812753 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
12812753 MGI
part of tenascin complex IPI
IPI: 通过物理相互作用推断
14709716 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

tenascin-N

TN-N

tenasin W

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tnn NCBI NCBI:63923