1. Gene
  2. Kdm7a - lysine (K)-specific demethylase 7A Gene

Kdm7a - lysine (K)-specific demethylase 7A Gene

种属: Mus musculus

同用名: Jhdm1d; mKIAA1718; A630082K20Rik

基因 ID: 338523 | 基因类型: protein coding

关于 Kdm7a

功能概要

Enables histone H3-methyl-lysine-9 demethylase activity and histone H3-tri/di-methyl-lysine-27 demethylase activity. Involved in histone H3-K27 demethylation; histone H3-K9 demethylation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleolus and nucleoplasm. Human ortholog(s) of this gene implicated in melanoma. Orthologous to human KDM7A (lysine demethylase 7A). [provided by Alliance of Genome Resources, Apr 2022]

Kdm7a 基因产物(1)

mRNA Protein Name
NM_001033430.4 NP_001028602.2 lysine-specific demethylase 7A
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H3K27me2/H3K27me3 demethylase activity IMP
IMP: 通过突变表型推断
20194436 MGI
enables histone H3K9 demethylase activity IMP
IMP: 通过突变表型推断
20194436 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
20194436 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lysine-specific demethylase 7A

[histone H3]-dimethyl-L-lysine9 demethylase 7A

jmjC domain-containing histone demethylation protein 1D

jumonji C domain-containing histone demethylase 1 homolog D

lysine-specific demethylase 7

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kdm7a NCBI NCBI:80853