1. Gene
  2. Cdc6 - cell division cycle 6 Gene

Cdc6 - cell division cycle 6 Gene

种属: Rattus norvegicus

基因 ID: 360621 | 基因类型: protein coding

关于 Cdc6

功能概要

Predicted to enable DNA replication origin binding activity; chromatin binding activity; and kinase binding activity. Involved in cellular response to peptide hormone stimulus; positive regulation of cyclin-dependent protein serine/threonine kinase activity; and positive regulation of fibroblast proliferation. Predicted to be located in several cellular components, including intercellular bridge; nucleoplasm; and spindle. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Orthologous to human CDC6 (cell division cycle 6). [provided by Alliance of Genome Resources, Apr 2022]

Cdc6 基因产物(1)

mRNA Protein Name
NM_001108298.1 NP_001101768.1 cell division control protein 6 homolog
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
18356301 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to angiotensin IEP
IEP: 通过表达模式推断
12063292 RGD
involved in cellular response to vasopressin IEP
IEP: 通过表达模式推断
12063292 RGD
involved in positive regulation of cyclin-dependent protein serine/threonine kinase activity IMP
IMP: 通过突变表型推断
22223646 RGD
involved in positive regulation of fibroblast proliferation IDA
IDA: 通过直接分析推断
22223646 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cell division control protein 6 homolog

cell division cycle 6 homolog

Cdc6 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Cdc6 D3ZRK7 Skp1 Rattus norvegicus Q6PEC4 18356301
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdc6 NCBI NCBI:990