2. Gene
  3. Tyrobp - transmembrane immune signaling adaptor Tyrobp Gene

Tyrobp - transmembrane immune signaling adaptor Tyrobp Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Karap

基因 ID: 361537 | 基因类型: protein coding

关于 Tyrobp

功能概要

Predicted to enable protein homodimerization activity and signaling receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; myeloid cell activation involved in immune response; and regulation of cytokine production. Predicted to act upstream of or within osteoclast differentiation and regulation of osteoclast development. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be active in cell surface. Biomarker of rheumatoid arthritis. Human ortholog(s) of this gene implicated in Nasu-Hakola disease. Orthologous to human TYROBP (transmembrane immune signaling adaptor TYROBP). [provided by Alliance of Genome Resources, Apr 2022]

Tyrobp 基因产物(1)

mRNA Protein Name
NM_212525.1 NP_997690.1 TYRO protein tyrosine kinase-binding protein precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
12077224 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

TYRO protein tyrosine kinase-binding protein

DAP12

DNAX-activation protein 12

Tyro protein tyrosine kinase binding protein

killer cell activating receptor-associated protein

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15309 TYROBP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21215 Tyrobp Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27731 Tyrobp Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tyrobp NCBI NCBI:7305
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