2. Gene
  3. UBE3A - Ube3a ubiquitin protein ligase E3A Gene

UBE3A - Ube3a ubiquitin protein ligase E3A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 361585 | 基因类型: protein coding

关于 UBE3A

功能概要

Predicted to enable transcription coactivator activity and ubiquitin protein Ligase activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; locomotory exploration behavior; and motor learning. Predicted to be located in cytosol and nucleus. Predicted to be part of Proteasome complex. Used to study Angelman syndrome. Human ortholog(s) of this gene implicated in Angelman syndrome. Orthologous to human UBE3A (ubiquitin protein Ligase E3A). [provided by Alliance of Genome Resources, Apr 2022]

UBE3A 基因产物(1)

mRNA Protein Name
NM_001191837.4 NP_001178766.1 ubiquitin-protein ligase E3A
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to brain-derived neurotrophic factor stimulus IEP
IEP: 通过表达模式推断
25867122 RGD
involved in locomotory exploration behavior IMP
IMP: 通过突变表型推断
32066685 RGD
involved in motor learning IMP
IMP: 通过突变表型推断
32066685 RGD
involved in negative regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
25867122 RGD
involved in positive regulation of Golgi lumen acidification IMP
IMP: 通过突变表型推断
23447592 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
24810662 RGD
involved in response to hydrogen peroxide IEP
IEP: 通过表达模式推断
17883392 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin-protein ligase E3A

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-148130 Rugonersen Activator 91.12% Phase 1
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148130A Rugonersen sodium 91.12% 否
HY-162683 (S)-PHA533533 Inhibitor 98.27% 否
HY-RS15368 UBE3A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20508 Ube3a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27016 Ube3a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens UBE3A NCBI NCBI:7337
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