1. Gene
  2. Spast - spastin Gene

Spast - spastin Gene

种属: Rattus norvegicus

同用名: Spg4

基因 ID: 362700 | 基因类型: protein coding

关于 Spast

功能概要

Predicted to enable microtubule-severing ATPase activity and tubulin binding activity. Predicted to be involved in several processes, including axonal transport; microtubule Cytoskeleton organization; and protein complex oligomerization. Predicted to be located in several cellular components, including cytosol; endoplasmic reticulum tubular network; and nucleus. Predicted to be active in microtubule Cytoskeleton. Predicted to colocalize with endoplasmic reticulum; endosome; and midbody. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 4. Orthologous to human SPAST (spastin). [provided by Alliance of Genome Resources, Apr 2022]

Spast 基因产物(1)

mRNA Protein Name
NM_001108702.2 NP_001102172.2 spastin
蛋白主名 其他名称

spastin

spastic paraplegia 4 (autosomal dominant

spastic paraplegia 4 (autosomal dominant

spastin)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Spast NCBI NCBI:6683
Mus musculus Spast NCBI NCBI:50850