VWC2 - von Willebrand factor C domain containing 2 Gene

中文名称：含 von Willebrand 因子 C 域 2

种属: Homo sapiens

同用名: UNQ739; PSST739

基因 ID: 375567 | 基因类型: protein coding

关于 VWC2

Cytogenetic location: 7p12.2 Genomic coordinates (GRCh38): 7:49,773,638-49,922,205 (from NCBI)

This gene has 1 transcript (splice variant), 201 orthologues and 19 paralogues. Biased expression in heart (RPKM 2.5), ovary (RPKM 2.4) and 3 other tissues.

功能概要

该基因编码一种分泌型骨形态发生蛋白拮抗剂。编码的蛋白质可能参与神经功能和发育，并可能在细胞粘附中起作用。[RefSeq 提供，2009 年 10 月]

This gene encodes a secreted bone morphogenic protein antagonist. The encoded protein is possibly involved in neural function and development and may have a role in cell adhesion.[provided by RefSeq, Oct 2009]

VWC2 基因产物(1)

mRNA	Protein	Name
NM_198570.5	NP_940972.2	brorin precursor

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VWC2 蛋白结构

VWC

0
100
200
300
325 a.a.

蛋白主名

其他名称

brorin

brain-specific chordin-like protein

VWC2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	VWC2	Q2TAL6	KRTAP10-8	Homo sapiens	P60410	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP10-8	Homo sapiens	P60410	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Array	32296183
种属内	VWC2	Q2TAL6	ADAMTSL4	Homo sapiens	Q6UY14-3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ADAMTSL4	Homo sapiens	Q6UY14-3	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP13-3	Homo sapiens	Q3SY46	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	KRTAP13-3	Homo sapiens	Q3SY46	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE3E	Homo sapiens	Q5T5B0	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE4A	Homo sapiens	Q5TA78	Y2H Array	32296183
种属内	VWC2	Q2TAL6	LCE4A	Homo sapiens	Q5TA78	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE4A	Homo sapiens	Q5TA78	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	LCE2D	Homo sapiens	Q5TA82	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	VASN	Homo sapiens	Q6EMK4	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ZNF774	Homo sapiens	Q6NX45	Y2H Array	32296183
种属内	VWC2	Q2TAL6	ZNF774	Homo sapiens	Q6NX45	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	ZNF774	Homo sapiens	Q6NX45	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ZNF497	Homo sapiens	Q6ZNH5	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	KPRP	Homo sapiens	Q5T749	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ZNF490	Homo sapiens	Q9ULM2	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ZNF696	Homo sapiens	Q9H7X3	Anti Tag CoIP	33961781
种属内	VWC2	Q2TAL6	ZNF696	Homo sapiens	Q9H7X3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ATPAF2	Homo sapiens	Q8N5M1	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	KRTAP13-2	Homo sapiens	Q52LG2	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP13-2	Homo sapiens	Q52LG2	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	KRTAP13-2	Homo sapiens	Q52LG2	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	SHFL	Homo sapiens	Q9NUL5-4	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	HAPLN2	Homo sapiens	Q9GZV7	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE1F	Homo sapiens	Q5T754	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE1A	Homo sapiens	Q5T7P2	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	LCE1A	Homo sapiens	Q5T7P2	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE1A	Homo sapiens	Q5T7P2	Y2H Array	32296183
种属内	VWC2	Q2TAL6	ZNF837	Homo sapiens	Q96EG3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE2C	Homo sapiens	Q5TA81	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE2C	Homo sapiens	Q5TA81	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	LCE2C	Homo sapiens	Q5TA81	Y2H Array	32296183
种属内	VWC2	Q2TAL6	GNE	Homo sapiens	Q9Y223-2	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ZNF319	Homo sapiens	Q9P2F9	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	NTM	Homo sapiens	Q9P121-3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE1C	Homo sapiens	Q5T751	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	LCE1C	Homo sapiens	Q5T751	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE1C	Homo sapiens	Q5T751	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP2-4	Homo sapiens	Q9BYR9	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	KRTAP2-4	Homo sapiens	Q9BYR9	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP2-4	Homo sapiens	Q9BYR9	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	PRPF31	Homo sapiens	Q8WWY3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	POU4F2	Homo sapiens	Q12837	Y2H Array	32296183
种属内	VWC2	Q2TAL6	POU4F2	Homo sapiens	Q12837	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	CRY2	Homo sapiens	Q49AN0	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	KANK2	Homo sapiens	Q63ZY3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ABHD15	Homo sapiens	Q6UXT9	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	CYSRT1	Homo sapiens	A8MQ03	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	CYSRT1	Homo sapiens	A8MQ03	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP5-9	Homo sapiens	P26371	Y2H Array	32296183
种属内	VWC2	Q2TAL6	KRTAP5-9	Homo sapiens	P26371	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	ZNF587	Homo sapiens	Q96SQ5	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	FAM90A1	Homo sapiens	Q86YD7	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	LCE3D	Homo sapiens	Q9BYE3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	TRAPPC14	Homo sapiens	Q8WVR3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	TRAPPC14	Homo sapiens	Q8WVR3	Y2H Array	32296183
种属内	VWC2	Q2TAL6	TRAPPC14	Homo sapiens	Q8WVR3	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	OTX1	Homo sapiens	P32242	Y2H Array	32296183
种属内	VWC2	Q2TAL6	OTX1	Homo sapiens	P32242	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	ZNF417	Homo sapiens	Q8TAU3	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	HOXA1	Homo sapiens	P49639	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	HOXA1	Homo sapiens	P49639	Y2H Array	32296183
种属内	VWC2	Q2TAL6	CNNM3	Homo sapiens	Q8NE01	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	FBXW5	Homo sapiens	Q969U6	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	SGTB	Homo sapiens	Q96EQ0	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	SGTB	Homo sapiens	Q96EQ0	Y2H Array	32296183
种属内	VWC2	Q2TAL6	SGTB	Homo sapiens	Q96EQ0	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	ENKD1	Homo sapiens	Q9H0I2	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	CATSPER1	Homo sapiens	Q8NEC5	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	SCNM1	Homo sapiens	Q9BWG6	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	FUCA2	Homo sapiens	Q9BTY2	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	FUCA2	Homo sapiens	Q9BTY2	Y2H Prey Pooling	32296183
种属内	VWC2	Q2TAL6	FUCA2	Homo sapiens	Q9BTY2	Y2H Array	32296183
种属内	VWC2	Q2TAL6	LCE3A	Homo sapiens	Q5TA76	Validated Y2H	32296183
种属内	VWC2	Q2TAL6	UBQLN2	Homo sapiens	Q9UHD9	Validated Y2H	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 VWC2 蛋白

目录号	产品名	蛋白编号	纯度
HY-P77506	Brorin/VWC2 Protein, Human (HEK293, His)	Q2TAL6 (S28-M325)	≥95%

关联疾病

疾病名称

别名

Tarsal-Carpal Coalition Syndrome

TCC	Tarsal Carpal Coalition Syndrome
Nog-Related-Symphalangism Spectrum Disorder

Craniodiaphyseal Dysplasia

CDD	Schaefer Stein Oshman Syndrome
Craniodiaphyseal Dysplasia, Dominant	Dominantly Inherited Craniodiaphyseal Dysplasia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS15732	VWC2 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS16429	VWC2L Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS20837	Vwc2 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS21805	Vwc2l Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS27351	Vwc2 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS28321	Vwc2l Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	VWC2	MGD	MGI:2442987
Canis familiaris	VWC2	VGNC	VGNC:52060
Rattus norvegicus	VWC2	RGD	RGD:1589624
Felis catus	VWC2	VGNC	VGNC:102729
Bos taurus	VWC2	VGNC	VGNC:36857
Macaca mulatta	VWC2	VGNC	VGNC:108452
Others	VWC2	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

VWC2 - von Willebrand factor C domain containing 2 Gene

关于 VWC2

功能概要

VWC2 基因产物(1)

VWC2 蛋白结构

VWC2 蛋白互作信息

重组 VWC2 蛋白

关联疾病

直系同源

热门区域

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VWC2 - von Willebrand factor C domain containing 2 Gene

关于 VWC2

功能概要

VWC2 基因产物(1)

VWC2 蛋白结构

VWC2 蛋白互作信息

重组 VWC2 蛋白

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z