2. Gene
  3. VWA5A - von Willebrand factor A domain containing 5A Gene

VWA5A - von Willebrand factor A domain containing 5A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 von Willebrand 因子 A 结构域 5A

种属: Homo sapiens

同用名: BCSC1; BCSC-1; LOH11CR2A

基因 ID: 4013 | 基因类型: protein coding

关于 VWA5A

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:124,115,450-124,147,721 (from NCBI)

This gene has 6 transcripts (splice variants), 115 orthologues and 11 paralogues. Ubiquitous expression in colon (RPKM 15.2), gall bladder (RPKM 14.6) and 24 other tissues.

功能概要

位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

VWA5A 基因产物(3)

mRNA Protein Name
NM_001130142.2 NP_001123614.1 von Willebrand factor A domain-containing protein 5A isoform 1
NM_014622.5 NP_055437.2 von Willebrand factor A domain-containing protein 5A isoform 1
NM_198315.3 NP_938057.1 von Willebrand factor A domain-containing protein 5A isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

VWA5A 蛋白结构

VIT

VIT: Vault protein inter-alpha-trypsin domain (14 - 130)

VWA_3

VWA_3: von Willebrand factor type A domain (283 - 443)

  • 0
  • 200
  • 400
  • 600
  • 786 a.a.
蛋白主名 其他名称

von Willebrand factor A domain-containing protein 5A

breast cancer suppressor candidate 1

VWA5A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
VWA5A O00534 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
种属内
VWA5A O00534 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
种属内
VWA5A O00534 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
种属内
VWA5A O00534 SPSB1 Homo sapiens Q96BD6
Validated Y2H
32296183
种属内
VWA5A O00534 SPSB1 Homo sapiens Q96BD6
Y2H Array
32296183
种属内
VWA5A O00534 SPSB1 Homo sapiens Q96BD6
Y2H Prey Pooling
32296183
种属内
VWA5A O00534 PRTFDC1 Homo sapiens Q9NRG1
Y2H Prey Pooling
32296183
种属内
VWA5A O00534 PRTFDC1 Homo sapiens Q9NRG1
Validated Y2H
32296183
种属内
VWA5A O00534 PRTFDC1 Homo sapiens Q9NRG1
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15728 VWA5A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus VWA5A VGNC VGNC:81094
Mus musculus VWA5A MGD MGI:1915026
Bos taurus VWA5A VGNC VGNC:36853
Macaca mulatta VWA5A VGNC VGNC:79963
Canis familiaris VWA5A VGNC VGNC:48322
Rattus norvegicus VWA5A RGD RGD:735145
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