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  2. YY2 - YY2 transcription factor Gene

YY2 - YY2 transcription factor Gene

中文名称:YY2 转录因子

种属: Homo sapiens

同用名: ZNF631

基因 ID: 404281 | 基因类型: protein coding

关于 YY2

Cytogenetic location: Xp22.12 Genomic coordinates (GRCh38): X:21,855,987-21,858,740 (from NCBI)

This gene has 1 transcript (splice variant), 21 orthologues and 2 paralogues.

功能概要

该基因编码的蛋白质是一种转录因子,在其 C 末端区域包含多个 Kruppel 样锌指。它同时具有激活和抑制结构域,因此它可以对靶基因的转录产生积极和消极的影响。该基因有一个无内含子的编码区,它似乎是由位于 14 号染色体上的相关 YY1 转录因子基因的逆转录转座产生的。[RefSeq 提供,2010 年 5 月]

The protein encoded by this gene is a transcription factor that includes several Kruppel-like zinc fingers in its C-terminal region. It possesses both activation and repression domains, and it can therefore have both positive and negative effects on the transcription of target genes. This gene has an intronless coding region, and it appears to have arisen by retrotransposition of the related YY1 transcription factor gene, which is located on chromosome 14. [provided by RefSeq, May 2010]

YY2 基因产物(1)

mRNA Protein Name
NM_206923.4 NP_996806.2 transcription factor YY2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
15087442 GOA
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
16260628 GOA
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
23332764 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
15087442 GOA
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16260628 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
16260628 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

YY2 蛋白结构

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (255 - 278)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (298 - 323)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (327 - 353)

  • 0
  • 100
  • 200
  • 300
  • 372 a.a.
蛋白主名 其他名称

transcription factor YY2

transcription factor yin yang 2

直系同源

种属 基因名 来源 基因 ID
Mus musculus YY2 MGD MGI:3837947
Rattus norvegicus YY2 RGD RGD:2324567